Boc-Phe-OMe
N-(tert-Butoxycarbonyl)-L-phenylalanine methyl ester (CAS 51987-73-6) is a protected amino acid derivative with a molecular weight of 279.33 g/mol. This compound serves as a crucial building block in peptide synthesis and organic chemistry. Its structure incorporates a Boc protecting group on the amine and a methyl ester on the carboxyl group of L-phenylalanine, facilitating controlled chemical reactions. Available from Tech Serve Solutions, it is primarily used in research and development settings.
- IUPAC
- N-(tert-Butoxycarbonyl)-L-phenylalanine methyl ester,Boc-L-phenylalanine methyl ester
- Synonyms
- N-(tert-Butoxycarbonyl)-L-phenylalanine methyl esterBoc-L-phenylalanine methyl ester
![Boc-Phe-OMe (C6H5CH2CH[NHCO2C(CH3)3]CO2CH3) — chemical structure, CAS 51987-73-6; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F51987-73-6.png&w=3840&q=75)
Peptide Synthesis
This Boc-protected phenylalanine derivative is a key intermediate in the solid-phase and solution-phase synthesis of peptides. The tert-butoxycarbonyl (Boc) group offers acid lability for deprotection, allowing sequential addition of amino acids.
Organic Synthesis
Utilised as a chiral building block in complex organic syntheses, its protected functional groups enable selective transformations. It is valuable for constructing molecules with specific stereochemistry.
Chemical Biology Research
Used in studies involving protein structure, enzyme mechanisms, and the development of peptidomimetics. Its well-defined structure aids in understanding biological interactions.
| Molecular weight | 279.33 |
|---|---|
| Linear formula | C6H5CH2CH[NHCO2C(CH3)3]CO2CH3 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]20/D −3.8±0.5°, c = 2% in methanol |
| Melting point | 36-40 °C(lit.)38-41 °C |

Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Flash point | 113 °C / 235.4 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36-41 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Phe-OMe used for?
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Boc-Phe-OMe is primarily used as a protected amino acid derivative in peptide synthesis and as a chiral building block in organic synthesis and chemical biology research.
What is the CAS number and molecular formula for Boc-Phe-OMe?
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The CAS number is 51987-73-6. The linear formula is C<sub>6</sub>H<sub>5</sub>CH<sub>2</sub>CH[NHCO<sub>2</sub>C(CH<sub>3</sub>)<sub>3</sub>]CO<sub>2</sub>CH<sub>3</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Phe-OMe with an assay of ≥98.0% (TLC). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for Boc-Phe-OMe?
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Boc-Phe-OMe is classified as a Warning substance (GHS07), causing serious eye irritation (H319). Handle with appropriate personal protective equipment, including eye protection, and avoid contact with skin and eyes. In case of eye contact, rinse cautiously with water for several minutes and seek medical advice if irritation persists.
How is Boc-Phe-OMe shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Boc-Phe-OMe, adhering to international shipping regulations for chemical transport.
How can I request a sample or quote for Boc-Phe-OMe?
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To request a sample or a quote for Boc-Phe-OMe, please contact our sales department through the details provided on the Tech Serve Solutions website.
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