Boc-Phe-OSu
Boc-Phe-OSu (CAS: 3674-06-4), also known as N-alpha-Boc-L-phenylalanine N-hydroxysuccinimide ester, is a protected amino acid derivative with the molecular formula C18H22N2O6. This compound serves as a crucial reagent in organic synthesis, particularly in peptide chemistry. It facilitates the controlled introduction of the phenylalanine residue into peptide chains, making it valuable for research and development in areas such as chemical biology and the synthesis of complex biomolecules.
- IUPAC
- Boc-L-phenylalanine N-hydroxysuccinimide ester
Peptide Synthesis
Boc-Phe-OSu is employed as an activated ester for the efficient coupling of N-alpha-Boc-L-phenylalanine to peptides. Its N-hydroxysuccinimide leaving group ensures good reactivity under mild conditions, facilitating amide bond formation.
Chemical Biology Research
This reagent is used in the synthesis of modified peptides and peptidomimetics for studying biological pathways and protein interactions. Its application allows for the precise incorporation of phenylalanine analogues into molecular probes.
Organic Synthesis
Beyond peptide synthesis, Boc-Phe-OSu can be utilized in various organic transformations requiring the introduction of a protected phenylalanine moiety. It serves as a versatile building block in the construction of complex organic molecules.
| Molecular weight | 362.38 |
|---|---|
| Empirical formula | C18H22N2O6 |
| Assay | ≥98.0% (HPLC) |
| Optical activity | [α]20/D −21.0±1°, c = 1% in dioxane |
| Storage temperature | −20°C |
| Melting point | 150-152 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Phe-OSu used for?
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Boc-Phe-OSu is primarily used as an activated ester for the synthesis of peptides and in chemical biology research for incorporating N-alpha-Boc-L-phenylalanine into molecular structures.
What is the CAS number and formula for Boc-Phe-OSu?
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The CAS number for Boc-Phe-OSu is 3674-06-4, and its empirical formula is C18H22N2O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Phe-OSu with a purity of ≥98.0% as determined by HPLC. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should Boc-Phe-OSu be handled and stored?
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Boc-Phe-OSu should be handled with appropriate personal protective equipment, including eyeshields and gloves. A P1/N95 respirator filter is recommended. Store at −20°C to maintain its integrity. The compound is classified under WGK Germany 3.
Is Boc-Phe-OSu available for export?
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Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals, including Boc-Phe-OSu.
How can I request a sample or quote for Boc-Phe-OSu?
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To request a sample or a quotation for Boc-Phe-OSu, please contact our sales team through the TSS website or via direct inquiry, providing your specific requirements.
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