Boc-Phe-ONp
Boc-Phe-ONp (CAS: 7535-56-0), with the molecular formula C20H22N2O6 and a molecular weight of 386.40 g/mol, is a protected amino acid derivative. Specifically, it is the 4-nitrophenyl ester of N-tert-butoxycarbonyl-L-phenylalanine. This compound serves as a valuable intermediate and reagent in peptide synthesis and chemical biology research, facilitating the controlled formation of peptide bonds.
- IUPAC
- Boc-L-phenylalanine 4-nitrophenyl ester
- Synonyms
- Boc-L-phenylalanine 4-nitrophenyl ester
Peptide Synthesis
Boc-Phe-ONp is utilised as an activated amino acid derivative in solid-phase and solution-phase peptide synthesis. The 4-nitrophenyl ester group acts as a good leaving group, allowing for efficient coupling with the N-terminus of a growing peptide chain.
Chemical Biology Research
This compound is employed in biochemical studies and the synthesis of modified peptides or peptidomimetics. Its structure allows for controlled incorporation into biomolecules for probing biological processes.
Organic Synthesis Intermediate
As a derivative of phenylalanine, Boc-Phe-ONp can be used as a building block in the synthesis of more complex organic molecules, including pharmaceuticals and fine chemicals.
| Molecular weight | 386.40 |
|---|---|
| Empirical formula | C20H22N2O6 |
| Assay | ≥99.0% (HPLC) |
| Optical activity | [α]20/D −21.5±0.5°, c = 2% in DMF |
| Storage temperature | −20°C |
| Melting point | 127-128 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Phe-ONp used for?
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Boc-Phe-ONp is primarily used as an activated amino acid derivative in peptide synthesis and as an intermediate in chemical biology research and organic synthesis.
What are the CAS number and formula for Boc-Phe-ONp?
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The CAS number is 7535-56-0, and the molecular formula is C20H22N2O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Phe-ONp with a purity of ≥99.0% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Boc-Phe-ONp be handled and stored?
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Handle Boc-Phe-ONp with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator filter (type N95 or P1). Store the material at −20°C.
Is Boc-Phe-ONp a controlled substance?
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The provided data does not indicate that Boc-Phe-ONp is a controlled substance.
How is Boc-Phe-ONp packed and shipped?
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Boc-Phe-ONp is carefully packed according to industry standards for chemical reagents and is available for export globally by Tech Serve Solutions.
How can I request a quote or sample for Boc-Phe-ONp?
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To request a quote or sample, please contact our sales department through the Tech Serve Solutions website or by phone.
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