Boc-Pip-OH
Boc-Pip-OH (CAS: 26250-84-0; C11H19NO4; MW: 229.27 g/mol) is a valuable derivative of pipecolinic acid. Utilised primarily in chemical synthesis and peptide chemistry, this compound serves as a protected amino acid building block. Its defined stereochemistry and the tert-Butoxycarbonyl (Boc) protecting group make it instrumental in constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and biologically active molecules. TSS supplies Boc-Pip-OH for research and development purposes.
- IUPAC
- (S)-(−)-1-(tert-Butoxycarbonyl)-2-piperidinecarboxylic acid,(S)-1-Boc-piperidine-2-carboxylic acid,N-Boc-L-pipecolinic acid
- Synonyms
- (S)-(−)-1-(tert-Butoxycarbonyl)-2-piperidinecarboxylic acid(S)-1-Boc-piperidine-2-carboxylic acidN-Boc-L-pipecolinic acid
Peptide Synthesis
Boc-Pip-OH serves as a crucial protected proline analogue in solid-phase and solution-phase peptide synthesis. Its incorporation allows for the introduction of conformational constraints and specific structural motifs into peptide chains.
Chiral Building Block
As a chiral molecule with defined stereochemistry, Boc-Pip-OH is employed as a stereospecific building block in the asymmetric synthesis of complex organic molecules and pharmaceutical intermediates.
Medicinal Chemistry Research
This compound is frequently used in medicinal chemistry programs for the synthesis of novel drug candidates. The piperidine ring and the Boc protecting group facilitate diverse derivatization strategies.
Chemical Biology
Boc-Pip-OH finds application in chemical biology for the synthesis of modified peptides or peptidomimetics used to probe biological pathways or develop biochemical tools.
| Molecular weight | 229.27 |
|---|---|
| Empirical formula | C11H19NO4 |
| Assay | 98% |
| Optical activity | [α]23/D −63.2°, c = 1 in acetic acid |
| Optical purity | ee: 98% (GLC) |
| Melting point | 122-126 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Pip-OH used for?
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Boc-Pip-OH is primarily used as a protected amino acid building block in peptide synthesis, chiral synthesis, medicinal chemistry research, and chemical biology applications.
What is the CAS number and formula for Boc-Pip-OH?
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The CAS number for Boc-Pip-OH is 26250-84-0, and its empirical formula is C11H19NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Pip-OH with a minimum assay of 98%. This product is intended for research and development use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should Boc-Pip-OH be handled?
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Handle Boc-Pip-OH with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. It is classified as a Warning substance (GHS07) with hazards H315, H319, and H335.
How is Boc-Pip-OH shipped and exported?
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Boc-Pip-OH is carefully packaged and exported globally by Tech Serve Solutions, adhering to all relevant shipping and customs regulations for chemical compounds.
How can I request a sample or quote for Boc-Pip-OH?
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To request a sample or quote for Boc-Pip-OH, please contact our sales team through the website or by phone, providing your details and the quantity required.
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