Boc-Phg-OH

CAS 2900-27-8C6H5CH(COOH)NHCOOC(CH3)3Chemical Synthesis

Boc-Phg-OH (CAS 2900-27-8) is an unnatural amino acid derivative, specifically N-tert-butoxycarbonyl-L-phenylglycine. With a molecular weight of 251.28 g/mol, it is a key building block in chemical synthesis and peptide chemistry. Its defined optical activity and high purity make it suitable for advanced research and development in chemical biology and the creation of complex peptide structures. TSS supplies this compound for laboratory and industrial applications.

IUPAC: Boc-L-α-phenylglycine
Synonyms: N-tert-butoxycarbonyl-L-phenylglycineBoc-L-phenylglycine

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Boc-Phg-OH (C6H5CH(COOH)NHCOOC(CH3)3) — chemical structure, CAS 2900-27-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical BiologyChemical SynthesisPeptide ChemistryPhenylglycine Derivatives

01 /Applications

Peptide Synthesis

Boc-Phg-OH serves as a crucial unnatural amino acid building block in solid-phase and solution-phase peptide synthesis. It allows for the introduction of phenylglycine residues, enhancing the structural diversity and properties of synthetic peptides.

Chemical Biology Research

This derivative is utilized in chemical biology to create modified peptides and peptidomimetics for probing biological pathways and protein interactions. Its incorporation can lead to peptides with altered stability, conformation, or receptor binding affinity.

Organic Synthesis

As a versatile chiral molecule, Boc-Phg-OH finds application in asymmetric synthesis and the development of novel organic compounds. It can be employed as a chiral auxiliary or a starting material for complex molecule construction.

Drug Discovery

In pharmaceutical research, Boc-Phg-OH is used in the synthesis of peptidomimetics and small molecules with potential therapeutic applications. Its unique structure can contribute to improved pharmacokinetic profiles or target engagement.

02 /Properties

Molecular weight	251.28
Linear formula	C6H5CH(COOH)NHCOOC(CH3)3
Assay	≥99.0% (T)
Optical activity	[α]20/D +144±2°, c = 1% in ethanol
Melting point	88-91 °C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

2900-27-8

MDL number

MFCD00065588

Beilstein registry

3592362

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Boc-Phg-OH used for?

Boc-Phg-OH is primarily used as an unnatural amino acid building block in peptide synthesis, chemical biology research, organic synthesis, and drug discovery for creating modified peptides and novel organic compounds.

What is the CAS number and formula for Boc-Phg-OH?

The CAS number for Boc-Phg-OH is 2900-27-8. Its linear formula is C 6 H 5 CH(COOH)NHCOOC(CH 3 ) 3 .

What grade and purity does Tech Serve Solutions supply for Boc-Phg-OH?

Tech Serve Solutions supplies Boc-Phg-OH with a purity of ≥99.0% (T). TSS does not represent this product as USP, BP, or EP grade.

How should Boc-Phg-OH be handled safely?

Handle Boc-Phg-OH with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation, and use a type N95 (US) or type P1 (EN143) respirator filter if necessary. This compound has a WGK Germany classification of 3.