Tris(4-methoxyphenyl)phosphine
Tris(4-methoxyphenyl)phosphine (CAS: 855-38-9) is a phosphine compound with the linear formula (CH3OC6H4)3P and a molecular weight of 352.36 g/mol. This organophosphorus compound is primarily utilised as a ligand in catalysis, particularly in cross-coupling reactions, and serves as a valuable building block in chemical synthesis. Its structure makes it suitable for applications in catalysis and inorganic chemistry, contributing to advancements in these fields.

Ligand in Catalysis
Tris(4-methoxyphenyl)phosphine functions as an electron-rich phosphine ligand, commonly employed in transition metal catalysis. It is particularly useful in facilitating various cross-coupling reactions, enhancing reaction efficiency and selectivity.
Organophosphorus Chemistry
As a trisubstituted phosphine, it is a key intermediate and reagent in organophosphorus chemistry. Its structure allows for diverse synthetic transformations, contributing to the development of new materials and pharmaceuticals.
Chemical Synthesis
This compound serves as a versatile reagent in organic synthesis. It can be incorporated into more complex molecular architectures, finding utility in academic research and industrial chemical development.
| Molecular weight | 352.36 |
|---|---|
| Linear formula | (CH3OC6H4)3P |
| Assay | 95% |
| Melting point | 131-134 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tris(4-methoxyphenyl)phosphine used for?
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Tris(4-methoxyphenyl)phosphine is used as a phosphine ligand in catalysis, particularly for cross-coupling reactions, and as a reagent in chemical synthesis and organophosphorus chemistry.
What is the CAS number and formula for Tris(4-methoxyphenyl)phosphine?
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The CAS number is 855-38-9 and the linear formula is (CH3OC6H4)3P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tris(4-methoxyphenyl)phosphine with an assay of 95%. This is typically considered a research or technical grade, and TSS does not represent it as USP, BP, or EP grade.
How should Tris(4-methoxyphenyl)phosphine be handled safely?
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Handling Tris(4-methoxyphenyl)phosphine requires appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation to avoid inhalation, as it can cause skin irritation, serious eye irritation, and respiratory irritation (H315, H319, H335).
Is Tris(4-methoxyphenyl)phosphine a controlled substance?
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The provided data does not indicate that Tris(4-methoxyphenyl)phosphine is a controlled substance.
How is Tris(4-methoxyphenyl)phosphine packed and shipped?
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Tris(4-methoxyphenyl)phosphine is carefully packed to ensure safe transit and is available for global export. Please contact us for specific shipping and packaging details.
How can I request a sample or quote for Tris(4-methoxyphenyl)phosphine?
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To request a sample or a quote for Tris(4-methoxyphenyl)phosphine, please use the contact form on our website or reach out to our sales department directly.
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