Tris(4-trifluoromethylphenyl)phosphine
Tris(4-trifluoromethylphenyl)phosphine (CAS: 13406-29-6) is a specialised organophosphorus compound with the linear formula ((CF3)C6H4)3P and a molecular weight of 466.28 g/mol. This phosphine derivative is primarily utilised as a ligand in transition metal catalysis and in general chemical synthesis. Its unique electronic properties, imparted by the trifluoromethyl groups, make it valuable for fine-tuning catalytic activity and selectivity in various organic transformations. TSS supplies this compound with a typical assay of 97%.
- IUPAC
- Tris(p-trifluoromethylphenyl)phosphine

Ligand in Homogeneous Catalysis
Tris(4-trifluoromethylphenyl)phosphine serves as an electron-deficient phosphine ligand in homogeneous catalysis. It is employed to modify the electronic and steric properties of metal centres, influencing the efficiency and selectivity of reactions such as cross-coupling and hydroformylation.
Chemical Synthesis Intermediate
This phosphine is a useful building block and reagent in complex organic synthesis. It can participate in various reactions, contributing to the construction of intricate molecular architectures relevant to pharmaceuticals and materials science.
Research and Development
Utilised in academic and industrial R&D settings, Tris(4-trifluoromethylphenyl)phosphine aids in the exploration of new catalytic systems and synthetic methodologies. Its specific properties allow for the investigation of reaction mechanisms and the development of novel chemical processes.
| Molecular weight | 466.28 |
|---|---|
| Linear formula | ((CF3)C6H4)3P |
| Assay | 97% |
| Melting point | 70-75 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tris(4-trifluoromethylphenyl)phosphine used for?
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Tris(4-trifluoromethylphenyl)phosphine is primarily used as a ligand in homogeneous catalysis and as an intermediate in chemical synthesis, particularly for research and development purposes.
What is the CAS number and formula for Tris(4-trifluoromethylphenyl)phosphine?
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The CAS number for Tris(4-trifluoromethylphenyl)phosphine is 13406-29-6. Its linear formula is ((CF3)C6H4)3P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tris(4-trifluoromethylphenyl)phosphine with a typical assay of 97%. We do not represent this product as meeting USP, BP, EP, or other pharmacopoeia standards.
How should Tris(4-trifluoromethylphenyl)phosphine be handled?
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Handle Tris(4-trifluoromethylphenyl)phosphine with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. Ensure adequate ventilation. Avoid breathing dust and contact with skin and eyes. Refer to the Safety Data Sheet for comprehensive handling information.
How is Tris(4-trifluoromethylphenyl)phosphine packed and shipped?
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Tris(4-trifluoromethylphenyl)phosphine is carefully packed to maintain its integrity during transit. As a global supplier, Tech Serve Solutions adheres to all relevant regulations for the export of chemical compounds.
How can I request a sample or quote for Tris(4-trifluoromethylphenyl)phosphine?
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To request a sample or a quotation for Tris(4-trifluoromethylphenyl)phosphine, please contact our sales team via the website or by phone. Provide your requirements, and we will respond promptly.
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