5-Chloroisatin
5-Chloroisatin (CAS: 17630-76-1), with the molecular formula C8H4ClNO2 and a molecular weight of 181.58 g/mol, is a halogenated heterocyclic compound. It serves as a valuable building block in chemical synthesis, particularly for the creation of more complex organic molecules. This compound is characterised by its indigo-like structure and the presence of a chlorine atom, making it a useful intermediate in the development of novel chemical entities.
- IUPAC
- 5-Chloro-1H-indole-2,3-dione
- Synonyms
- 5-Chloro-1H-indole-2,3-dione
Synthesis of Schiff Bases
5-Chloroisatin is utilised as a precursor in the synthesis of Schiff bases. For example, it has been reacted with 2-methyl-4-nitroaniline to form specific imine derivatives, demonstrating its utility in creating complex nitrogen-containing organic compounds.
Intermediate in Organic Synthesis
As a halogenated indole derivative, 5-Chloroisatin is an important intermediate for organic chemists. Its reactive sites allow for various functionalisation reactions, facilitating the construction of diverse molecular architectures relevant to medicinal chemistry and materials science.
Research Chemical
This compound is employed in laboratory research for exploring new synthetic routes and developing novel chemical structures. Its availability makes it a convenient starting material for academic and industrial R&D projects.
| Molecular weight | 181.58 |
|---|---|
| Empirical formula | C8H4ClNO2 |
| Assay | 97% |
| Application | 5-Chloroisatin was used in synthesis of Schiff base by reaction with 2-methyl-4-nitroaniline1. |
| Melting point | 254-258 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chloroisatin used for?
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5-Chloroisatin (CAS: 17630-76-1) is primarily used as a building block in organic synthesis and the preparation of Schiff bases. It serves as an intermediate in chemical research and development.
What are the CAS number and formula for 5-Chloroisatin?
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The CAS number for 5-Chloroisatin is 17630-76-1, and its empirical formula (Hill notation) is C8H4ClNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Chloroisatin with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for 5-Chloroisatin?
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5-Chloroisatin is a Warning substance (GHS07) that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is 5-Chloroisatin packed and shipped?
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5-Chloroisatin is carefully packed to ensure stability during transit. Tech Serve Solutions exports fine chemicals globally, adhering to all relevant shipping regulations.
How can I request a sample or quote for 5-Chloroisatin?
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To request a sample or obtain a quotation for 5-Chloroisatin, please contact our sales department via the website or directly through the provided contact information.
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