(R)-(+)-3-Methoxy-2-methyl-3-oxopropylzinc bromide solution
(R)-(+)-3-Methoxy-2-methyl-3-oxopropylzinc bromide solution (CAS 343338-26-1) is an organozinc halide reagent with a molecular weight of 246.42 g/mol. Supplied as a 0.5 M solution in THF, it is primarily utilised in organic synthesis for the formation of carbon-carbon bonds. Its chiral nature makes it valuable in asymmetric synthesis, enabling the stereoselective construction of complex molecules. This reagent is a key building block in the development of pharmaceuticals and advanced materials.
Asymmetric Synthesis
This chiral organozinc reagent is employed in stereoselective reactions to construct enantiomerically enriched organic molecules. It facilitates the introduction of specific stereocenters in pharmaceutical intermediates and complex natural products.
Carbon-Carbon Bond Formation
Utilized in cross-coupling reactions, such as Negishi coupling, to form new carbon-carbon bonds. This is a fundamental transformation in the synthesis of complex organic structures.
Pharmaceutical Intermediate Synthesis
Serves as a valuable building block in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its specific stereochemistry can be critical for biological activity.
Organometallic Chemistry
As an organozinc halide, it is a versatile reagent in organometallic chemistry, participating in various metal-catalyzed transformations and synthetic methodologies.
| Molecular weight | 246.42 |
|---|---|
| Linear formula | CH3O2CCH(CH3)CH2ZnBr |
| Density | 0.968 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-3-Methoxy-2-methyl-3-oxopropylzinc bromide solution used for?
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(R)-(+)-3-Methoxy-2-methyl-3-oxopropylzinc bromide solution is primarily used in organic synthesis, particularly in asymmetric synthesis and carbon-carbon bond formation reactions, and as an intermediate in pharmaceutical synthesis.
What is the CAS number and formula for this compound?
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The CAS number is 343338-26-1 and the linear formula is CH3O2CCH(CH3)CH2ZnBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.5 M solution in THF. We do not represent this product as USP, BP, or EP grade; it is intended for research and chemical synthesis purposes.
What are the safety considerations for handling this product?
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This product is flammable and can cause serious eye irritation and respiratory irritation. It is also suspected of causing cancer and may form explosive peroxides. Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources. Refer to the Safety Data Sheet for detailed handling information.
How is this product shipped and exported?
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This product is classified under UN 2924, 8(3) / PGII, indicating it is a corrosive and flammable liquid. It is shipped and exported in compliance with international regulations for hazardous materials.
How can I request a sample or quote?
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To request a sample or quote, please contact our sales department through the website or by phone, providing the product name and CAS number.
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