(R)-(+)-3-Chloro-1-phenyl-1-propanol
(R)-(+)-3-Chloro-1-phenyl-1-propanol (CAS 100306-33-0) is a chiral alcohol with the linear formula ClCH2CH2CH(C6H5)OH and a molecular weight of 170.64 g/mol. As a valuable asymmetric synthesis building block, it is frequently employed in the creation of complex organic molecules. Its specific stereochemistry makes it particularly useful in enantioselective synthesis pathways within the pharmaceutical and fine chemical industries.
- IUPAC
- α-(2-Chloroethyl)benzyl alcohol,(R)-(+)-α-(2-Chloroethyl)benzyl alcohol,(R)-(+)-3-Chloro-1-phenylpropanol
Chiral Building Block in Organic Synthesis
This compound serves as a key chiral intermediate in the synthesis of more complex organic molecules. Its defined stereochemistry allows for precise control in the formation of new chiral centres, essential for pharmaceuticals and advanced materials.
Precursor for Pharmaceutical Intermediates
The molecule's structure, featuring a chiral alcohol and a chloroalkyl side chain, makes it a suitable starting material for the synthesis of various pharmaceutical intermediates. It is integral to creating active pharmaceutical ingredients (APIs) requiring specific stereoisomers.
Asymmetric Synthesis Reagent
Utilised in asymmetric synthesis, (R)-(+)-3-Chloro-1-phenyl-1-propanol enables the production of enantiomerically enriched compounds. This is crucial for drugs where only one enantiomer exhibits therapeutic activity or has a favourable safety profile.
| Molecular weight | 170.64 |
|---|---|
| Linear formula | ClCH2CH2CH(C6H5)OH |
| Assay | 98% |
| Optical activity | [α]24/D +26°, c = 1 in chloroform |
| Optical purity | ee: 99% (GLC) |
| Melting point | 58-60 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-3-Chloro-1-phenyl-1-propanol used for?
+
(R)-(+)-3-Chloro-1-phenyl-1-propanol is primarily used as a chiral building block and intermediate in organic synthesis, particularly in the pharmaceutical and fine chemical sectors for creating enantiomerically pure compounds.
What are the CAS number and formula for (R)-(+)-3-Chloro-1-phenyl-1-propanol?
+
The CAS number is 100306-33-0, and its linear formula is ClCH2CH2CH(C6H5)OH.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (R)-(+)-3-Chloro-1-phenyl-1-propanol with an assay of 98% and an optical purity of ee: 99%. This is a technical/research grade, and TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
What are the safety and handling precautions for this chemical?
+
This compound is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, in a well-ventilated area.
Is (R)-(+)-3-Chloro-1-phenyl-1-propanol a controlled substance?
+
The provided data does not indicate that (R)-(+)-3-Chloro-1-phenyl-1-propanol is a controlled substance.
How is this chemical packed, shipped, and exported?
+
Tech Serve Solutions offers expert packaging, shipping, and global export services for chemicals like (R)-(+)-3-Chloro-1-phenyl-1-propanol, adhering to all necessary regulations for safe and compliant transport.
How can I request a sample or quote?
+
To request a sample or a quote for (R)-(+)-3-Chloro-1-phenyl-1-propanol, please contact our sales team through the website or by direct inquiry, providing your requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis