(R)-(+)-3-Benzyloxy-1,2-propanediol
(R)-(+)-3-Benzyloxy-1,2-propanediol (CAS: 56552-80-8) is a chiral building block with the molecular formula C10H14O3 and a molecular weight of 182.22 g/mol. This glycerol derivative is primarily utilised in complex organic synthesis. Its applications include the preparation of cyclopropyl chirons for 2,3-methanoamino acids and the synthesis of biologically significant phospholipid analogs and petrosynes.
- IUPAC
- (R)-Glycerol 1-benzyl ether,3-O-Benzyl-sn-glycerol,3-Benzyl-sn-glycerol
- Synonyms
- (R)-Glycerol 1-benzyl ether3-O-Benzyl-sn-glycerol3-Benzyl-sn-glycerol

Synthesis of Cyclopropyl Chirons
(R)-(+)-3-Benzyloxy-1,2-propanediol is employed in the synthesis of cyclopropyl chirons. These intermediates are crucial for the preparation of 2,3-methanoamino acids, a class of non-proteinogenic amino acids.
Chiral Building Block for Natural Product Synthesis
This compound serves as a valuable chiral building block in the total synthesis of complex natural products, such as petrosynes. Its defined stereochemistry is essential for achieving the correct molecular architecture.
Preparation of Phospholipid Analogs
It is utilised in the synthesis of biologically important phospholipid analogs. These synthetic analogs are instrumental in research studies investigating cell membrane structure and function.
| Molecular weight | 182.22 |
|---|---|
| Linear formula | C6H5CH2OCH2CH(OH)CH2OH |
| Assay | 99% |
| Optical activity | [α]20/D +5.5°, c = 20 in chloroform |
| Storage temperature | 2-8°C |
| Application | Employed in the synthesis of a cyclopropyl chiron used in the preparation of 2,3-methanoamino acids.1 Chiral building block in the synthesis of petrosynes2 and biologically important phospholipid analogs.3,4 |
| Melting point | 25-29 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-3-Benzyloxy-1,2-propanediol used for?
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(R)-(+)-3-Benzyloxy-1,2-propanediol is used as a chiral building block in organic synthesis, specifically for preparing cyclopropyl chirons, 2,3-methanoamino acids, petrosynes, and phospholipid analogs.
What is the CAS number and molecular formula for (R)-(+)-3-Benzyloxy-1,2-propanediol?
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The CAS number is 56552-80-8, and its molecular formula is C10H14O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-3-Benzyloxy-1,2-propanediol with an assay of 99%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should (R)-(+)-3-Benzyloxy-1,2-propanediol be handled?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use a suitable respirator filter (type N95 or P1). Refer to the Safety Data Sheet for detailed handling instructions.
Is (R)-(+)-3-Benzyloxy-1,2-propanediol a controlled substance?
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Based on the provided data, there is no indication that (R)-(+)-3-Benzyloxy-1,2-propanediol is a controlled substance.
How is (R)-(+)-3-Benzyloxy-1,2-propanediol packed and shipped?
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This chemical is typically stored at 2-8°C. Shipping and export are handled by Tech Serve Solutions in compliance with all relevant regulations for fine chemicals.
How can I request a sample or quote for (R)-(+)-3-Benzyloxy-1,2-propanediol?
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To request a sample or quote, please contact the Tech Serve Solutions sales team via the website or by phone, providing the product name and CAS number.
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