(R)-(+)-3-(Dimethylamino)pyrrolidine
(R)-(+)-3-(Dimethylamino)pyrrolidine (CAS: 132958-72-6), with the chemical formula C6H14N2 and a molecular weight of 114.19 g/mol, is a chiral heterocyclic compound. It serves as a valuable building block in organic synthesis, particularly in asymmetric catalysis and the development of complex molecules. Its enantiopure nature makes it instrumental in stereoselective transformations.
- IUPAC
- (3R)-N,N-Dimethyl-3-pyrrolidinamine
Chiral Auxiliary in Asymmetric Synthesis
This enantiomerically pure pyrrolidine derivative can be employed as a chiral auxiliary to induce stereoselectivity in various chemical reactions, facilitating the synthesis of enantiomerically enriched products.
Precursor for Pharmaceutical Intermediates
Its unique structure makes it a key intermediate in the synthesis pathways of complex active pharmaceutical ingredients (APIs), where precise stereochemistry is critical.
Ligand Development
The compound's nitrogen atoms can coordinate with metal centres, making it a potential component in the design of novel chiral ligands for catalysis.
| Molecular weight | 114.19 |
|---|---|
| Empirical formula | C6H14N2 |
| Assay | 95% |
| Boiling point | 166 °C/760 mmHg(lit.) |
| Density | 0.899 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4650(lit.) |
| Optical activity | [α]20/D +14°, c = 1 in ethanol |
Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 51 °C / 123.8 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-22-37/38-41 |
| Safety statements (S) | 26-36/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-3-(Dimethylamino)pyrrolidine used for?
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(R)-(+)-3-(Dimethylamino)pyrrolidine is primarily used as a chiral building block in asymmetric synthesis and as a precursor for pharmaceutical intermediates and potentially in ligand development for catalysis.
What is the CAS number and chemical formula for this compound?
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The CAS number is 132958-72-6 and the chemical formula is C6H14N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-3-(Dimethylamino)pyrrolidine with an assay of 95%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should (R)-(+)-3-(Dimethylamino)pyrrolidine be handled safely?
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This compound is classified as flammable and causes severe eye damage, skin irritation, and respiratory irritation. Handle with appropriate personal protective equipment including eyeshields, face shields, gloves, and respiratory protection in a well-ventilated area. Refer to the Safety Data Sheet for full hazard information and handling procedures.
How is this chemical shipped and exported?
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As a supplier and exporter of fine chemicals, Tech Serve Solutions ships (R)-(+)-3-(Dimethylamino)pyrrolidine according to international regulations for hazardous materials. Specific packaging and shipping details will be provided upon inquiry.
How can I request a sample or quote?
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To request a sample or a quote for (R)-(+)-3-(Dimethylamino)pyrrolidine, please contact our sales team via the website or email, providing your specific requirements.
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