(R)-(+)-3-Hydroxypiperidine hydrochloride
(R)-(+)-3-Hydroxypiperidine hydrochloride (CAS: 198976-43-1) is a chiral building block with the chemical formula C5H11NO · HCl and a molecular weight of 137.61 g/mol. This white to off-white solid is primarily utilised as a starter material in asymmetric synthesis, particularly for the development of pharmaceutical compounds. Its specific stereochemistry makes it valuable in creating enantiomerically pure substances.

Chiral Building Block in Pharmaceutical Synthesis
Serves as a crucial starting material for synthesising complex pharmaceutical intermediates and active pharmaceutical ingredients. Its defined stereochemistry is essential for the development of enantiomerically pure drugs.
Asymmetric Synthesis
Employed in asymmetric synthesis to introduce chirality into target molecules. This is vital for creating compounds with specific biological activities and reduced side effects.
Heterocyclic Chemistry
Utilised as a valuable component in the synthesis of various heterocyclic compounds, including piperidine derivatives, which are common motifs in medicinal chemistry.
| Molecular weight | 137.61 |
|---|---|
| Empirical formula | C5H11NO · HCl |
| Assay | 98% |
| Optical activity | [α]20/D +8.6°, c = 2 in methanol |
| Application | Starter for (R)-(+)-3-pyrrolidyl benzilates with pharmaceutical applications.1 |
| Melting point | 195-196 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-3-Hydroxypiperidine hydrochloride used for?
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(R)-(+)-3-Hydroxypiperidine hydrochloride is used as a starter material in asymmetric synthesis, particularly for pharmaceutical applications, and as a chiral building block in chemical synthesis.
What is the CAS number and chemical formula?
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The CAS number for (R)-(+)-3-Hydroxypiperidine hydrochloride is 198976-43-1, and its chemical formula is C5H11NO · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-3-Hydroxypiperidine hydrochloride with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should (R)-(+)-3-Hydroxypiperidine hydrochloride be handled?
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Handle with appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation, as it can cause skin, eye, and respiratory irritation (H315-H319-H335).
Is (R)-(+)-3-Hydroxypiperidine hydrochloride a controlled substance?
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The provided data does not indicate that (R)-(+)-3-Hydroxypiperidine hydrochloride is a controlled substance.
How is this product packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to all relevant regulations for safe transport.
How can I request a sample or quote for (R)-(+)-3-Hydroxypiperidine hydrochloride?
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Please contact the Tech Serve Solutions sales team directly via our website or listed contact details to request a sample or a quotation.
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