1-Trimethylsilyl-1-hexyne
1-Trimethylsilyl-1-hexyne (CAS: 3844-94-8) is a valuable organic building block with the linear formula CH3(CH2)3C≡CSi(CH3)3 and a molecular weight of 154.32 g/mol. This trimethylsilyl-protected alkyne is a versatile intermediate in organic synthesis, particularly in carbon-carbon bond formation reactions. It serves as a key reagent for introducing specific alkynyl functionalities into complex molecules, finding utility in pharmaceutical research and material science development.
Organic Synthesis Intermediate
Used as a precursor in various organic transformations, including Sonogashira couplings and click chemistry, to build complex molecular architectures.
Pharmaceutical Research
Facilitates the synthesis of novel drug candidates and intermediates by enabling precise alkyne incorporation.
Material Science
Contributes to the development of new polymers and functional materials through its unique reactive properties.
Building Block for Complex Molecules
Provides a reliable route to incorporate a hexynyl moiety protected by a trimethylsilyl group, aiding in regioselective reactions.
| Molecular weight | 154.32 |
|---|---|
| Linear formula | CH3(CH2)3C≡CSi(CH3)3 |
| Assay | 99% |
| Boiling point | 65 °C/35 mmHg(lit.) |
| Density | 0.764 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.431(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 50 °C / 122 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Trimethylsilyl-1-hexyne used for?
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1-Trimethylsilyl-1-hexyne is primarily used as an intermediate in organic synthesis for constructing complex molecules, particularly in pharmaceutical research and material science.
What is the CAS number and chemical formula for 1-Trimethylsilyl-1-hexyne?
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The CAS number is 3844-94-8, and the linear formula is CH3(CH2)3C≡CSi(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Trimethylsilyl-1-hexyne with a purity of 99% (assay). This product is not intended for USP, BP, EP, or any pharmacopoeia, food, or nutraceutical use.
How should 1-Trimethylsilyl-1-hexyne be handled safely?
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1-Trimethylsilyl-1-hexyne is a flammable liquid and vapour (H226) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and in a well-ventilated area. Ensure protection against ignition sources.
Is 1-Trimethylsilyl-1-hexyne shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 1-Trimethylsilyl-1-hexyne, adhering to all relevant shipping regulations.
How can I request a quote or sample?
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To request a quote or sample of 1-Trimethylsilyl-1-hexyne, please contact our sales team through the website or by phone.
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