1-Trifluoroacetyl piperidine
1-Trifluoroacetyl piperidine (CAS: 340-07-8; Formula: C7H10F3NO; MW: 181.16) is a valuable heterocyclic building block used in chemical synthesis. Its trifluoroacetyl group offers unique reactivity, making it a key intermediate in the preparation of complex molecules. Applications include the synthesis of photoreactive probes, photoactive mannosides, and potential anticonvulsant compounds. Tech Serve Solutions supplies this chemical with an assay of 97%.
- IUPAC
- 2,2,2-Trifluoro-1-(piperidin-1-yl)ethanone
- Synonyms
- 2,2,2-Trifluoro-1-(piperidin-1-yl)ethanone
Synthesis of Photoreactive Probes
This compound serves as a reactant in creating photoreactive probes designed to differentiate binding sites of noncompetitive GABA receptor antagonists.
Preparation of Photoactive Glycoconjugates
It is utilised in the synthesis of photoactive a-mannosides and mannosyl peptides, essential for biochemical research.
Development of Cytochrome P450 Inactivators
1-Trifluoroacetyl piperidine is employed in the synthesis of compounds that inactivate human cytochrome P450 2B6.
Anticonvulsant Research
It is a precursor for the synthesis of hydroxyamides with potential anticonvulsant properties.
| Molecular weight | 181.16 |
|---|---|
| Empirical formula | C7H10F3NO |
| Assay | 97% |
| Density | 1.226 g/mL at 25 °C |
| Refractive index | n20/D 1.4171 |
| Application | Reactant for synthesis of:• Photoreactive probes that differentiate the binding sites of noncompetitive GABA receptor antagonists1• Photoactive a-mannosides and mannosyl peptides2• Inactivators of human cytochrome P450 2B63• Photoaffinity labeled fusidic acid analogues4• Hydroxyamides as anticonvulsants5• ET-18-OCH3 with antiproliferative properties6 |
Hazard statements
- H300Fatal if swallowed
- H319Causes serious eye irritation
- H400Very toxic to aquatic life
Precautionary statements
- P264Wash thoroughly after handling
- P273Avoid release to the environment
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 76 °C / 168.8 °F |
| Transport (UN / ADR) | UN 2810 6.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-50 |
| Safety statements (S) | 45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Trifluoroacetyl piperidine used for?
+
1-Trifluoroacetyl piperidine is used as a reactant in chemical synthesis for creating photoreactive probes, photoactive glycoconjugates, inactivators of human cytochrome P450 2B6, photoaffinity labeled fusidic acid analogues, anticonvulsants, and ET-18-OCH3 with antiproliferative properties.
What is the CAS number and molecular formula for 1-Trifluoroacetyl piperidine?
+
The CAS number is 340-07-8 and the molecular formula is C7H10F3NO.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 1-Trifluoroacetyl piperidine with an assay of 97%. This is a technical/research grade material and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should 1-Trifluoroacetyl piperidine be handled safely?
+
1-Trifluoroacetyl piperidine is classified as Danger (GHS06, GHS09) with hazards H300 (Fatal if swallowed) and H400 (Very toxic to aquatic life). Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection. Avoid release to the environment.
Is 1-Trifluoroacetyl piperidine available for export?
+
Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 1-Trifluoroacetyl piperidine.
How can I request a sample or quote for 1-Trifluoroacetyl piperidine?
+
To request a sample or quote, please contact the Tech Serve Solutions sales team through the website or designated contact channels.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis