Boc-Phe(4-CN)-OH
Boc-Phe(4-CN)-OH (CAS: 131724-45-3) is a protected unnatural amino acid derivative with the molecular formula C15H18N2O4 and a molecular weight of 290.31 g/mol. This compound serves as a valuable building block in chemical synthesis and peptide chemistry. It is frequently utilised in the development of modified peptides and in research applications within chemical biology. Tech Serve Solutions supplies this reagent with a high degree of purity for demanding research and development projects.
- IUPAC
- Boc-4-cyano-L-phenylalanine
- Synonyms
- Boc-4-cyano-L-phenylalanine

Peptide Synthesis
Boc-Phe(4-CN)-OH is employed as a protected unnatural amino acid in solid-phase and solution-phase peptide synthesis. Its incorporation allows for the creation of peptides with modified side chains for research into structure-activity relationships.
Chemical Biology Research
This compound finds application in chemical biology for the synthesis of custom peptides and peptidomimetics. These molecules are used to probe biological pathways and protein interactions.
Drug Discovery and Development
As a derivative of phenylalanine, it can be incorporated into potential drug candidates. The cyano group offers a point for further chemical modification or can influence pharmacokinetic properties.
Organic Synthesis Intermediate
Beyond peptide chemistry, Boc-Phe(4-CN)-OH serves as a versatile intermediate in complex organic synthesis. It provides a chiral building block with protected functionality for constructing elaborate molecular architectures.
| Molecular weight | 290.31 |
|---|---|
| Empirical formula | C15H18N2O4 |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Phe(4-CN)-OH primarily used for?
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Boc-Phe(4-CN)-OH is primarily used as a protected unnatural amino acid building block in peptide synthesis and chemical biology research for creating modified peptides and peptidomimetics.
What are the CAS number and molecular formula for Boc-Phe(4-CN)-OH?
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The CAS number for Boc-Phe(4-CN)-OH is 131724-45-3, and its molecular formula is C15H18N2O4.
What grade and purity does Tech Serve Solutions supply for Boc-Phe(4-CN)-OH?
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Tech Serve Solutions supplies Boc-Phe(4-CN)-OH with an assay of ≥98.0% determined by TLC. This is suitable for research and synthesis purposes; TSS does not represent this product as USP, BP, or EP grade.
How should Boc-Phe(4-CN)-OH be handled safely?
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When handling Boc-Phe(4-CN)-OH, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. Respiratory protection, such as a type N95 (US) or type P1 (EN143) respirator filter, should be used. The compound is classified under WGK Germany 3, indicating a significant hazard to water.
Does Tech Serve Solutions export Boc-Phe(4-CN)-OH?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Boc-Phe(4-CN)-OH, and can fulfil export orders worldwide.
How can I request a sample or quote for Boc-Phe(4-CN)-OH?
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To request a sample or a quote for Boc-Phe(4-CN)-OH, please contact the Tech Serve Solutions sales team through our website or by direct enquiry, providing your specific requirements.
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