(S)-(−)-1-(1-Naphthyl)ethylamine
(S)-(−)-1-(1-Naphthyl)ethylamine (CAS: 10420-89-0) is a chiral amine with the molecular formula C <sub>10</sub>H<sub>7</sub>CH(CH<sub>3</sub>)NH<sub>2</sub> and a molecular weight of 171.24 g/mol. This compound serves as a valuable chiral building block in organic synthesis, particularly in the preparation of specialized solvating agents for enantiodiscrimination. Its applications are primarily focused on advanced chemical research and analytical methodologies.
- IUPAC
- (S)-(−)-α-Methyl-1-naphthalenemethylamine
- Synonyms
- (S)-(−)-α-Methyl-1-naphthalenemethylamine

Chiral Thiourea Solvating Agent Preparation
This amine is employed in the synthesis of chiral thiourea solvating agents. These agents are effective in the enantiodiscrimination of α-hydroxy and α-amino acids using <sup>1</sup>H NMR spectroscopy.
Asymmetric Synthesis
As a chiral amine, it functions as a key intermediate or building block in asymmetric synthesis, enabling the stereoselective construction of complex molecules.
Derivatization Reagent
It can be utilised as a derivatization reagent, particularly in analytical chemistry for techniques such as HPLC, to enhance the detection or separation of chiral compounds.
| Molecular weight | 171.24 |
|---|---|
| Linear formula | C10H7CH(CH3)NH2 |
| Assay | ≥98.5% (GC) |
| Boiling point | 153 °C/11 mmHg(lit.) |
| Density | 1.067 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.623(lit.) |
| Optical purity | enantiomeric excess: ≥98.5% |
| Application | Employed in a preparation of a chiral thiourea solvating agent useful for enantiodiscrimination of α-hydroxy and α-amino acids by 1H NMR.1 |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-1-(1-Naphthyl)ethylamine used for?
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(S)-(−)-1-(1-Naphthyl)ethylamine is used in the preparation of chiral thiourea solvating agents for enantiodiscrimination of α-hydroxy and α-amino acids by <sup>1</sup>H NMR and as a chiral building block in asymmetric synthesis.
What are the CAS number and formula for (S)-(−)-1-(1-Naphthyl)ethylamine?
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The CAS number is 10420-89-0 and the molecular formula is C <sub>10</sub>H<sub>7</sub>CH(CH<sub>3</sub>)NH<sub>2</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-1-(1-Naphthyl)ethylamine with an assay of ≥98.5% (GC) and an enantiomeric excess of ≥98.5%. We do not represent this product as USP, BP, or EP grade.
How should (S)-(−)-1-(1-Naphthyl)ethylamine be handled safely?
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This compound is a warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Ensure adequate ventilation, wear appropriate personal protective equipment including eyeshields and gloves, and use a suitable respirator filter (type ABEK).
Is this product controlled or scheduled?
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The provided data does not indicate that (S)-(−)-1-(1-Naphthyl)ethylamine is a controlled or scheduled substance.
How is this chemical exported and shipped?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. We adhere to all relevant international shipping and export regulations for hazardous materials.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales team through the website or by phone, providing the product name and CAS number (10420-89-0).
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