Potassium thioacetate
Potassium thioacetate (CAS: 10387-40-3), with the molecular formula CH3COSK and a molar mass of 114.21 g/mol, is a key reagent in organic synthesis. It is primarily utilised in palladium-mediated coupling reactions involving aryl halides and triflates. This process effectively yields S-arylthioacetates and related derivatives, making it a valuable tool for creating complex organic molecules in research and development settings.
- IUPAC
- Ethanethioic acid potassium salt,Thioacetic acid potassium salt,Thiolacetic acid potassium salt
- Synonyms
- Ethanethioic acid potassium saltThioacetic acid potassium saltThiolacetic acid potassium salt
S-Arylthioacetate Synthesis
Potassium thioacetate serves as a crucial nucleophile in palladium-catalysed cross-coupling reactions. It reacts with aryl halides and triflates to form carbon-sulfur bonds, specifically producing S-arylthioacetates.
Preparation of Organic Sulphur Compounds
This reagent facilitates the introduction of thioacetate groups into organic molecules. These thioacetate derivatives can be further manipulated to synthesise a variety of sulphur-containing organic compounds for diverse applications.
Research and Development Reagent
As a versatile synthetic reagent, Potassium thioacetate is employed in academic and industrial research laboratories for the development of novel synthetic methodologies and the exploration of new chemical entities.
| Molecular weight | 114.21 |
|---|---|
| Linear formula | CH3COSK |
| Assay | ≥98.0% (RT) |
| Application | Palladium mediated coupling with aryl halides and triflates leading to S-arylthioacetates and derivatives.1 |
| Melting point | 173-176 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3335 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Potassium thioacetate used for?
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Potassium thioacetate (CAS: 10387-40-3) is primarily used in palladium-mediated coupling reactions with aryl halides and triflates to synthesise S-arylthioacetates and related derivatives. It functions as a synthetic reagent in organic chemistry.
What is the CAS number and formula for Potassium thioacetate?
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The CAS number for Potassium thioacetate is 10387-40-3, and its linear formula is CH3COSK.
What grade and purity does Tech Serve Solutions supply for Potassium thioacetate?
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Tech Serve Solutions supplies Potassium thioacetate with a minimum assay of ≥98.0% (RT). This product is not supplied as USP, BP, EP or other pharmacopoeial grades.
How should Potassium thioacetate be handled safely?
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Potassium thioacetate is a warning substance that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, in a well-ventilated area.
How is Potassium thioacetate packed and shipped by TSS?
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Potassium thioacetate is carefully packed according to safety and transport regulations. TSS exports this chemical globally to meet the needs of researchers and industries worldwide.
How can I request a quote or sample for Potassium thioacetate?
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To request a quote or a sample of Potassium thioacetate, please contact the TSS sales team through our website or directly via email/phone. Our team will be pleased to assist you.
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