Bis(2-dichlorophosphinophenyl)ether
Bis(2-dichlorophosphinophenyl)ether (CAS 1293994-89-4; C12H8Cl4OP2; molar mass 371.95 g/mol) is an organophosphorus building block in which two reactive dichlorophosphino (PCl2) groups are held on a diphenyl ether backbone. Supplied as a research-grade solid of about 95% assay (melting point 62-66 C), it serves chiefly as a precursor for the synthesis of ether-bridged diphosphine ligands and other organophosphorus compounds used in homogeneous catalysis. It is a corrosive material requiring careful handling.
- Synonyms
- Bis(2-dichlorophosphinophenyl)etherBis(2-(dichlorophosphino)phenyl) etherOxybis(2,1-phenylene)bis(dichlorophosphine)CAS 1293994-89-4MFCD13182461
Diphosphine ligand synthesis
The two reactive P-Cl bonds allow controlled substitution with organolithium, Grignard or amine reagents to construct ether-bridged bidentate phosphine ligands on a diaryl ether scaffold. This makes it a convenient backbone precursor for tailored P-donor ligand families.
Organophosphorus chemistry
As a difunctional chlorophosphine, it is a versatile intermediate for installing two phosphorus centres in a single, geometrically defined framework. It is used in research laboratories to access phosphines, phosphine oxides and related derivatives.
Homogeneous catalysis precursors
Ligands derived from this compound can be coordinated to transition metals to form catalyst complexes for cross-coupling and related transformations. It therefore supports catalyst development programmes in catalysis and inorganic chemistry.
Research and method development
The compound is offered as a research-grade reagent for laboratory-scale synthesis, ligand screening and exploratory organophosphorus work. It is not represented for pharmaceutical or food use.
| Molecular weight | 371.95 |
|---|---|
| Empirical formula | C12H8Cl4OP2 |
| Assay | 95% |
| Storage temperature | 2-8°C |
| Melting point | 62-66 °C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 3261 8 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bis(2-dichlorophosphinophenyl)ether used for?
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It is used mainly as an organophosphorus building block for synthesising ether-bridged diphosphine ligands and related phosphorus compounds. Such ligands are employed in homogeneous (transition-metal) catalysis. The two reactive dichlorophosphino groups make it a flexible precursor for laboratory ligand and catalyst development.
What is the CAS number and molecular formula of Bis(2-dichlorophosphinophenyl)ether?
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The CAS number is 1293994-89-4 and the molecular formula is C12H8Cl4OP2 (Hill notation), with a molecular weight of 371.95 g/mol. The MDL number is MFCD13182461. Its reported melting point is 62-66 C.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a research/technical-grade reagent with an assay of approximately 95%. We do not represent it as USP, BP or EP / pharmacopoeia grade. A current Certificate of Analysis and Safety Data Sheet are provided with each consignment, and specific assay requirements can be confirmed at the time of enquiry.
What are the safety and handling hazards of Bis(2-dichlorophosphinophenyl)ether?
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It is classified under GHS05 with the signal word Danger and hazard statement H314: causes severe skin burns and eye damage. It is corrosive and moisture-sensitive. Handle only with suitable protective gloves, eye/face protection and clothing (P280); if in eyes, rinse cautiously with water for several minutes and remove contact lenses if present (P305+P351+P338); and seek immediate medical attention (P310). Always consult the full SDS before use.
How is Bis(2-dichlorophosphinophenyl)ether stored, packed, shipped and exported?
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It is recommended to be stored refrigerated at 2-8 C in tightly closed, moisture-protected containers. For transport it is classified as UN 3261, Class 8 (corrosive), Packing Group III. Tech Serve Solutions packs it in appropriate sealed laboratory containers and exports worldwide in compliance with applicable dangerous-goods (ADR/IMDG/IATA) regulations, with documentation arranged to suit the destination.
How do I request a sample or a quote?
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Contact Tech Serve Solutions with the product name, CAS number 1293994-89-4 and your required quantity, grade and destination. We will respond with availability, lead time, packing options and export documentation, along with a Certificate of Analysis and Safety Data Sheet on request.
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