1-(3-Methylphenyl)-2-oxo-3-pyrrolidinecarboxylic acid
1-(3-Methylphenyl)-2-oxo-3-pyrrolidinecarboxylic acid (CAS 618070-31-8) is a heterocyclic pyrrolidine building block with the molecular formula C12H13NO3 and a molar mass of 219.24 g/mol. It is a crystalline solid (melting point 100-104 °C) that pairs a 2-oxopyrrolidinone ring bearing a carboxylic acid with an N-linked meta-tolyl group. Tech Serve Solutions supplies it as a research-grade reagent for chemical synthesis, where it serves as a versatile scaffold and intermediate in medicinal and discovery chemistry.
- Synonyms
- 1-(3-Methylphenyl)-2-oxo-3-pyrrolidinecarboxylic acid2-Oxo-1-(3-methylphenyl)-3-pyrrolidinecarboxylic acid1-(m-Tolyl)-2-oxopyrrolidine-3-carboxylic acid2-Oxo-1-(m-tolyl)pyrrolidine-3-carboxylic acidCAS 618070-31-8MFCD03932874
Heterocyclic building block
Functions as a pyrrolidinone-based scaffold in chemical synthesis. The combination of a lactam ring, a free carboxylic acid and an N-aryl substituent offers multiple handles for further elaboration.
Pharmaceutical and discovery intermediate
Used as an intermediate and template in medicinal chemistry and structure-activity studies. Its 2-oxopyrrolidine (gamma-lactam) core is a recurring motif in bioactive molecule design.
Carboxylic acid coupling partner
The pendant carboxylic acid supports amide bond formation, esterification and related coupling chemistry, enabling rapid generation of analogues and conjugates.
Laboratory reagent for research and development
Supplied as a reagent for exploratory synthesis, route scouting and small-scale preparation in academic and industrial laboratories.
| Molecular weight | 219.24 |
|---|---|
| Empirical formula | C12H13NO3 |
| Assay | 97% |
| Melting point | 100-104 °C(lit.) |
Hazard statements
- H301Toxic if swallowed
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-43 |
| Safety statements (S) | 36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(3-Methylphenyl)-2-oxo-3-pyrrolidinecarboxylic acid used for?
+
It is used primarily as a heterocyclic building block and intermediate in chemical synthesis. The 2-oxopyrrolidine ring, free carboxylic acid and N-(3-methylphenyl) group make it a useful scaffold for medicinal chemistry, analogue preparation and general research applications.
What is the CAS number and molecular formula of 1-(3-Methylphenyl)-2-oxo-3-pyrrolidinecarboxylic acid?
+
The CAS number is 618070-31-8 and the molecular formula is C12H13NO3, with a molecular weight of 219.24 g/mol. The MDL number is MFCD03932874 and the reported melting point is 100-104 °C.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this compound at a typical assay of 97%, as a technical/research-grade reagent for synthesis. We do not represent it as a USP, BP or EP pharmacopoeial grade. A certificate of analysis can be provided with each batch on request.
What are the safety and handling requirements?
+
The material is classified GHS06 with the signal word Danger. The hazard statements are H301 (toxic if swallowed) and H317 (may cause an allergic skin reaction). Handle with suitable gloves, eye and face protection and a dust mask (type N95 or equivalent); avoid ingestion and skin contact, and follow the precautionary statements P280 and P301+P310. Always consult the Safety Data Sheet before use.
How is 1-(3-Methylphenyl)-2-oxo-3-pyrrolidinecarboxylic acid packed, shipped and exported?
+
It is packed in securely sealed, labelled containers appropriate to the order quantity, from gram to bulk scale. The product is classified for transport as UN 2811, Class 6.1, Packing Group III, and is shipped worldwide in accordance with applicable dangerous-goods regulations, accompanied by an SDS and certificate of analysis.
How do I request a sample or quote?
+
Contact Tech Serve Solutions with your required quantity, purity and destination, quoting CAS 618070-31-8. We will respond with availability, lead time, documentation and a formal quotation, and can arrange a sample where appropriate.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis