Bis(2-(bis(diethylamino)phosphino)phenyl) ether
Bis(2-(bis(diethylamino)phosphino)phenyl) ether (CAS 391208-78-9; C28H48N4OP2; molar mass 518.65 g/mol) is an air- and moisture-sensitive bidentate aminophosphine in which two diethylamino-substituted phosphino groups are held on a diphenyl ether backbone. This polydentate phosphorus ligand is used in coordination chemistry and homogeneous catalysis as a precursor and chelating donor for transition-metal complexes. Tech Serve Solutions supplies it at 95% assay for research and synthesis.
- IUPAC
- Bis(2-(bis(diethylamido)phosphino)phenyl) ether
- Synonyms
- Bis(2-(bis(diethylamino)phosphino)phenyl) etherBis(2-(bis(diethylamido)phosphino)phenyl) etherCAS 391208-78-9C28H48N4OP2MFCD13182462

Phosphine ligand for homogeneous catalysis
Serves as a bidentate, ether-bridged phosphorus ligand for preparing transition-metal complexes. Its chelating geometry supports the design of catalysts for coordination and organometallic studies.
Aminophosphine building block
The P–N (diethylamino) bonds provide reactive sites for converting the phosphorus centres into other phosphine, phosphonite or phosphoramidite derivatives. This makes it a versatile intermediate in ligand synthesis.
Coordination and inorganic chemistry research
Used to study chelation, metal–ligand bonding and complex stability with a rigid diphenyl ether spacer. Suited to academic and industrial coordination-chemistry programmes.
Chemical synthesis reagent
Applied as a specialist reagent in laboratory-scale synthesis where a polydentate phosphine donor is required. Handling is carried out under inert, anhydrous conditions.
| Molecular weight | 518.65 |
|---|---|
| Empirical formula | C28H48N4OP2 |
| Assay | 95% |
| Refractive index | n20/D 1.565 |
| Storage temperature | 2-8°C |


Hazard statements
- H261In contact with water releases flammable gas
- H314Causes severe skin burns and eye damage
Precautionary statements
- P231Handle under inert gas
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
- P422
| Flash point | >110 °C / >230 °F |
|---|---|
| Water hazard class (WGK, DE) | nwg |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 14/15-34 |
| Safety statements (S) | 26-36/37/39-43-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bis(2-(bis(diethylamino)phosphino)phenyl) ether used for?
+
It is used mainly as a bidentate aminophosphine ligand in coordination chemistry and homogeneous catalysis, where it chelates transition metals through its two phosphorus donor atoms. It also serves as a building block for synthesising related phosphine and phosphoramidite ligands.
What is the CAS number and molecular formula of Bis(2-(bis(diethylamino)phosphino)phenyl) ether?
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The CAS number is 391208-78-9 and the molecular formula is C28H48N4OP2, with a molecular weight of 518.65 g/mol. Its MDL number is MFCD13182462.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound at 95% assay as a research and synthesis grade material (refractive index n20/D 1.565). We do not represent it as USP, BP or EP pharmacopoeia grade; it is intended for research, catalysis and chemical synthesis use.
What are the safety and handling requirements?
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The compound is classified under GHS with signal word Danger (GHS02, GHS05). It carries H261 (in contact with water releases flammable gas) and H314 (causes severe skin burns and eye damage), and reacts violently with water. Handle under dry inert atmosphere, keep away from moisture, wear protective gloves, eye and face protection, and store at 2–8°C.
How is Bis(2-(bis(diethylamino)phosphino)phenyl) ether packed, shipped and exported?
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It is packed in sealed, moisture-excluding containers appropriate to the order quantity and refrigerated storage at 2–8°C, with labelling and documentation that reflect its flammable and corrosive GHS classification. As an air- and moisture-sensitive material it is consigned in line with applicable dangerous-goods transport rules for international export.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and packing, and we will respond with availability, lead time and export terms. Samples may be available subject to stock and the safety constraints of this air- and moisture-sensitive compound.
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