Potassium thiophene-2-trifluoroborate
Potassium thiophene-2-trifluoroborate (CAS: 906674-55-3, C4H3BF3KS) is an organotrifluoroborate salt and a key reagent in modern organic synthesis. It is primarily utilised in various cross-coupling reactions, including Suzuki, Negishi, and nickel-catalysed couplings. Its stability and reactivity make it a valuable surrogate for boronic acids in complex molecule construction. Tech Serve Solutions supplies this compound for research and development purposes.
Cross-Coupling Reactions
This organotrifluoroborate serves as a versatile coupling partner in a range of transition-metal catalysed reactions. It is particularly effective in Suzuki-Miyaura, Negishi, and nickel-catalysed cross-coupling methodologies for forming carbon-carbon bonds.
C-O Bond Formation
It can participate in the activation of C-O bonds in phenolic derivatives, enabling novel synthetic pathways for functionalisation. This application is crucial in the synthesis of complex organic molecules.
Boronic Acid Surrogate
Potassium thiophene-2-trifluoroborate offers advantages over traditional boronic acids, such as enhanced stability towards air and moisture. This makes it a reliable reagent in synthetic schemes requiring robust boronate species.
| Molecular weight | 190.04 |
|---|---|
| Empirical formula | C4H3BF3KS |
| Application | Organotrifluoroborate involved in:• A variety of cross-coupling reactions1, Negishi cross coupling2, Nickel-catalyzed cross-coupling3, and Suzuki cross-coupling4,5• C-O activation of phenol derivatives6Organotrifluoroborates as versatile and stable boronic acid surrogates. |
| Melting point | 245-265 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | nwg |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Potassium thiophene-2-trifluoroborate used for?
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Potassium thiophene-2-trifluoroborate is employed in various cross-coupling reactions, including Negishi, Nickel-catalyzed, and Suzuki couplings, and for C-O activation of phenol derivatives.
What is the CAS number and formula for Potassium thiophene-2-trifluoroborate?
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The CAS number is 906674-55-3 and the empirical formula (Hill notation) is C4H3BF3KS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research and development. The specific grade and purity are available upon request. We do not represent this product as USP, BP, or EP grade.
How should Potassium thiophene-2-trifluoroborate be handled?
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Handle with care. This compound may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Ensure adequate ventilation and wear appropriate personal protective equipment, including gloves and eye protection. Avoid breathing dust.
Is Potassium thiophene-2-trifluoroborate exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Potassium thiophene-2-trifluoroborate, serving customers worldwide.
How can I request a quote or sample?
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To request a quote or sample, please use the contact form on our website or contact our sales department directly, referencing the product name and CAS number.
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