Potassium trans-styryltrifluoroborate
Potassium trans-styryltrifluoroborate (CAS: 201852-49-5) is an organoboron compound with the formula C6H5(CH)2BF3K and a molecular weight of 210.05 g/mol. This white solid serves as a valuable reactant in various organic synthesis applications, particularly in cross-coupling reactions and the preparation of complex organic molecules. Its utility extends to functional group transformations and the synthesis of biologically relevant compounds.
- IUPAC
- Potassium trifluoro(E)-2-phenyl-1-ethenylborate,Potassium trifluoro(E)-2-phenylethenylborate
- Synonyms
- Potassium trifluoro(E)-2-phenyl-1-ethenylboratePotassium trifluoro(E)-2-phenylethenylborate
Suzuki-Miyaura Cross-Coupling Reactions
Potassium trans-styryltrifluoroborate is employed as a key nucleophilic coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds for the synthesis of diverse organic structures.
Enantioselective Total Synthesis
It has been utilised in the enantioselective total synthesis of natural products such as naseseazines A and B, showcasing its role in constructing complex chiral molecules.
Metal-Free Chlorodeboronation
This compound participates in metal-free chlorodeboronation reactions, offering a synthetic route for introducing chlorine atoms into organic frameworks.
Preparation of Aryl Ketones and Weinreb Amides
It serves as a precursor for the preparation of aryl ketones via Lewis acid-catalyzed nucleophilic substitution and for Weinreb amides through palladium-catalyzed cross-coupling.
| Molecular weight | 210.05 |
|---|---|
| Linear formula | C6H5(CH)2BF3K |
| Application | Reactant for:• Suzuki-Miyaura cross-coupling1,2• Enantioselective total synthesis of naseseazines A and B via regioselective Friedel-Crafts based arylative dimerization3• Metal-free chlorodeboronation reactions4• Preparation of aryl ketones via Lewis acid-catalyzed nucleophilic substitution5• Preparation of Weinreb amides by palladium-catalyzed cross-coupling reactions6 |
| Melting point | >300 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Potassium trans-styryltrifluoroborate used for?
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Potassium trans-styryltrifluoroborate is used as a reactant in organic synthesis, notably in Suzuki-Miyaura cross-coupling reactions, enantioselective total synthesis, metal-free chlorodeboronation, and the preparation of aryl ketones and Weinreb amides.
What are the CAS number and formula for Potassium trans-styryltrifluoroborate?
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The CAS number is 201852-49-5 and the linear formula is C6H5(CH)2BF3K.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a research-grade material. We do not represent it as USP, BP, or EP grade.
How should Potassium trans-styryltrifluoroborate be handled?
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Handle with care to avoid dust formation. Use a dust mask (N95 or equivalent), safety eyeshields, and gloves. This compound is an irritant to the skin, eyes, and respiratory tract (H315, H319, H335).
How is this chemical packed and exported?
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We ensure secure packaging for all our fine chemicals, pharmaceutical intermediates, and laboratory reagents, adhering to international shipping regulations for export.
How can I request a quote or sample?
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Please contact our sales team via the website or by phone to request a quotation or to arrange for a sample.
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