(2-Chloro-5-pyridyl)methylzinc chloride solution
(2-Chloro-5-pyridyl)methylzinc chloride solution (CAS: 352530-36-0, Formula: C6H5Cl2NZn) is an organozinc halide reagent. With a molecular weight of 227.41 g/mol, this solution, typically 0.5 M in THF, is primarily utilised in organic synthesis for the formation of carbon-carbon bonds. Its reactivity makes it a valuable tool in the construction of complex molecules, particularly in the development of pharmaceutical intermediates and other fine chemicals.
Organic Synthesis Reagent
Utilised in various cross-coupling reactions to introduce the (2-chloro-5-pyridyl)methyl moiety into target molecules. This is crucial for building complex organic frameworks.
Heterocyclic Chemistry
Serves as a key building block in the synthesis of substituted pyridines and other heteroaromatic compounds, which are common structural motifs in pharmaceuticals and agrochemicals.
Organozinc Halide Chemistry
Acts as a nucleophilic organozinc reagent, participating in reactions with electrophiles to form new carbon-carbon bonds under mild conditions.
| Molecular weight | 227.41 |
|---|---|
| Empirical formula | C6H5Cl2NZn |
| Boiling point | 65 °C |
| Density | 0.992 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2-Chloro-5-pyridyl)methylzinc chloride solution used for?
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(2-Chloro-5-pyridyl)methylzinc chloride solution is used in organic synthesis, particularly in cross-coupling reactions and for the construction of heterocyclic compounds.
What are the CAS number and formula for this product?
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The CAS number is 352530-36-0 and the empirical formula (Hill notation) is C6H5Cl2NZn.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a 0.5 M solution in THF. We do not claim USP, BP, or EP grade unless explicitly stated in the product specifications. For specific purity details, please refer to the product's Certificate of Analysis.
How should (2-Chloro-5-pyridyl)methylzinc chloride solution be handled and stored?
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This compound is flammable (H225) and can cause serious eye irritation (H319) and respiratory irritation (H335). It is suspected of causing cancer (H351) and may form explosive peroxides. Store at 2-8°C and handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources.
Is this product regulated or controlled?
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The provided safety data does not indicate a controlled or scheduled substance status. However, regulations can vary by jurisdiction; please consult your local authorities.
How is this product shipped and exported?
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(2-Chloro-5-pyridyl)methylzinc chloride solution is shipped under UN 2056, Hazard Class 3, Packing Group II. Tech Serve Solutions is experienced in exporting fine chemicals globally, adhering to all relevant shipping regulations.
How can I request a sample or a quote?
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To request a sample or a quote, please visit the 'Contact Us' section of the Tech Serve Solutions website or contact our sales team directly.
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