2-Chloro-3,6-difluorobenzaldehyde
2-Chloro-3,6-difluorobenzaldehyde (CAS: 261762-39-4) is a fluorinated aromatic aldehyde with the linear formula ClC<sub>6</sub>H<sub>2</sub>(F)<sub>2</sub>CHO and a molecular weight of 176.55 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in the development of complex molecules within the pharmaceutical and agrochemical industries. Its specific substitution pattern offers unique reactivity for introducing fluorinated aryl moieties into target structures, facilitating research and development.
- Synonyms
- ClC6H2(F)2CHO

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs), where the difluorinated chlorobenzaldehyde structure can impart desirable pharmacokinetic properties.
Agrochemical Development
Serves as a key intermediate in the creation of novel pesticides and herbicides, leveraging the unique electronic effects of fluorine substituents for enhanced efficacy.
Material Science Research
Explored as a precursor for specialised polymers and functional materials requiring fluorinated aromatic components.
Organic Synthesis Building Block
A versatile reagent for introducing a chloro-difluorophenyl group into various organic frameworks through reactions involving the aldehyde functionality.
| Molecular weight | 176.55 |
|---|---|
| Linear formula | ClC6H2(F)2CHO |
| Assay | 96% |
| Melting point | 46-50 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-3,6-difluorobenzaldehyde used for?
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2-Chloro-3,6-difluorobenzaldehyde is primarily used as a building block in organic synthesis, particularly for creating intermediates in the pharmaceutical and agrochemical industries, as well as in material science research.
What is the CAS number and molecular formula for 2-Chloro-3,6-difluorobenzaldehyde?
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The CAS number is 261762-39-4 and the linear formula is ClC<sub>6</sub>H<sub>2</sub>(F)<sub>2</sub>CHO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-3,6-difluorobenzaldehyde with an assay of 96%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Chloro-3,6-difluorobenzaldehyde be handled?
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Handle with appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, and gloves. Ensure good ventilation, avoid breathing dust/fume/gas/mist/vapours/spray, and avoid contact with skin and eyes. Specific precautionary statements include P261 and P305 + P351 + P338.
Does TSS export 2-Chloro-3,6-difluorobenzaldehyde?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Chloro-3,6-difluorobenzaldehyde.
How can I request a quote or sample for 2-Chloro-3,6-difluorobenzaldehyde?
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To request a quote or sample, please contact our sales department through the website or by phone, providing the product name and CAS number (261762-39-4).
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