2-Chloro-3,5-difluorophenol
2-Chloro-3,5-difluorophenol (CAS: 206986-81-4), with the linear formula ClC₆H₂(F)₂OH and a molecular weight of 164.54 g/mol, is a halogenated phenol. This compound serves as a valuable building block in organic synthesis, particularly within the fine chemical and pharmaceutical sectors. Its specific structure allows for diverse chemical transformations, contributing to the development of novel molecules and materials.
- Synonyms
- ClC6H2(F)2OH

Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of complex organic molecules. Its fluorinated and chlorinated aromatic structure provides reactive sites for further functionalisation in multi-step syntheses.
Pharmaceutical Research
A building block for the creation of potential pharmaceutical drug candidates. The presence of fluorine atoms can significantly influence a molecule's lipophilicity, metabolic stability, and binding affinity.
Agrochemical Development
Employed in the research and development of new agrochemical compounds. Fluorinated phenols can impart unique properties relevant to pesticides and herbicides.
Materials Science
Potentially used in the development of specialised polymers or materials where its specific halogenation pattern can confer desired properties such as thermal stability or flame retardancy.
| Molecular weight | 164.54 |
|---|---|
| Linear formula | ClC6H2(F)2OH |
| Assay | 98% |
| Boiling point | 76 °C/37 mmHg(lit.) |
| Melting point | 45-46 °C(lit.) |


Hazard statements
- H228Flammable solid
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 66 °C / 150.8 °F |
| Transport (UN / ADR) | UN 1325 4.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26-33-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-3,5-difluorophenol used for?
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2-Chloro-3,5-difluorophenol is primarily used as a building block in organic synthesis, including pharmaceutical research, agrochemical development, and potentially in materials science.
What is the CAS number and formula for 2-Chloro-3,5-difluorophenol?
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The CAS number for 2-Chloro-3,5-difluorophenol is 206986-81-4, and its linear formula is ClC₆H₂(F)₂OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-3,5-difluorophenol with a minimum assay of 98%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Chloro-3,5-difluorophenol be handled safely?
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Handling requires appropriate personal protective equipment, including eye shields, gloves, and respiratory protection (dust mask type N95 or N100, or P1/P3 filters), due to its classification as flammable solid, skin irritant, eye irritant, and respiratory irritant (H228, H315, H319, H335).
Is 2-Chloro-3,5-difluorophenol packed and exported by TSS?
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Yes, Tech Serve Solutions specialises in supplying and exporting fine chemicals like 2-Chloro-3,5-difluorophenol globally.
How can I request a quote or sample?
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Please use the contact form on our website or call us to request a quote or a sample of 2-Chloro-3,5-difluorophenol.
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