(−)-Lobeline hydrochloride
(−)-Lobeline hydrochloride (CAS: 134-63-4) is a chemical compound with the formula C22H27NO2 · HCl and a molecular weight of 373.92 g/mol. As a bioactive small molecule, it primarily functions as a cholinergic agent and has historical applications in research related to neurotransmission and cell signaling. Its properties make it valuable in various chemical synthesis pathways, particularly those involving chiral building blocks.
- IUPAC
- α-Lobeline hydrochloride,L-Lobeline hydrochloride
- Synonyms
- α-Lobeline hydrochlorideL-Lobeline hydrochloride

Neuroscience Research
This compound serves as a valuable tool in neuroscience research, particularly for studying cholinergic pathways and neurotransmitter receptor interactions. It can be used to investigate the mechanisms of neurocommunication and related physiological processes.
Chemical Synthesis
As a chiral building block and heterocyclic compound, (–)-Lobeline hydrochloride is utilised in complex organic synthesis. Its structure facilitates its incorporation into novel molecular architectures for diverse research applications.
Pharmacological Studies
It is employed in pharmacological studies to understand the effects of cholinergic agonists and their potential roles in biological systems. Research may explore its interactions with various receptors and signalling cascades.
| Molecular weight | 373.92 |
|---|---|
| Empirical formula | C22H27NO2 · HCl |
| Assay | 98% |
| Optical activity | [α]20/D −56.8°, c = 2 in H2O |
| Melting point | 183-185 °C (dec.)(lit.) |

Hazard statements
- H301Toxic if swallowed
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 1544 6.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/25 |
| Safety statements (S) | 36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (–)-Lobeline hydrochloride used for?
+
(–)-Lobeline hydrochloride is primarily used as a research chemical in neuroscience and pharmacology to study cholinergic pathways and neurotransmission. It also serves as a chiral building block in chemical synthesis.
What is the CAS number and chemical formula for (–)-Lobeline hydrochloride?
+
The CAS number is 134-63-4 and the chemical formula is C22H27NO2 · HCl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (–)-Lobeline hydrochloride with an assay of 98%. This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or any pharmacopoeia grade.
How should (–)-Lobeline hydrochloride be handled safely?
+
(–)-Lobeline hydrochloride is classified as toxic if swallowed and toxic if inhaled (H301-H331). Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator cartridge. Ensure adequate ventilation. Refer to the Safety Data Sheet for full handling instructions.
Is (–)-Lobeline hydrochloride a controlled substance?
+
The provided data does not indicate that (–)-Lobeline hydrochloride is a controlled substance. However, users are advised to consult local regulations.
How is (–)-Lobeline hydrochloride packed, shipped, and exported?
+
This product is packed in accordance with international shipping regulations for hazardous materials (UN 1544, Class 6.1). Tech Serve Solutions is an experienced global exporter of fine chemicals.
How can I request a sample or quote for (–)-Lobeline hydrochloride?
+
To request a sample or quote, please contact our sales team via the website or direct email, providing your contact details and the quantity required.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis