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(−)-Lobeline hydrochloride

CAS 134-63-4C22H27NO2 · HClChemical Synthesis

(−)-Lobeline hydrochloride (CAS: 134-63-4) is a chemical compound with the formula C22H27NO2 · HCl and a molecular weight of 373.92 g/mol. As a bioactive small molecule, it primarily functions as a cholinergic agent and has historical applications in research related to neurotransmission and cell signaling. Its properties make it valuable in various chemical synthesis pathways, particularly those involving chiral building blocks.

IUPAC
α-Lobeline hydrochloride,L-Lobeline hydrochloride
Synonyms
α-Lobeline hydrochlorideL-Lobeline hydrochloride
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(−)-Lobeline hydrochloride (C22H27NO2 · HCl) — chemical structure, CAS 134-63-4; Chemistry, fine chemical supplied by Tech Serve Solutions
AgonistsAsymmetric SynthesisBioactive Small MoleculesCell BiologyChemical SynthesisChiral Building BlocksCholinergicsHeterocyclic Building BlocksNeuroscienceNeurotransmission
01 /Applications

Neuroscience Research

This compound serves as a valuable tool in neuroscience research, particularly for studying cholinergic pathways and neurotransmitter receptor interactions. It can be used to investigate the mechanisms of neurocommunication and related physiological processes.

Chemical Synthesis

As a chiral building block and heterocyclic compound, (–)-Lobeline hydrochloride is utilised in complex organic synthesis. Its structure facilitates its incorporation into novel molecular architectures for diverse research applications.

Pharmacological Studies

It is employed in pharmacological studies to understand the effects of cholinergic agonists and their potential roles in biological systems. Research may explore its interactions with various receptors and signalling cascades.

02 /Properties
Molecular weight373.92
Empirical formulaC22H27NO2 · HCl
Assay98%
Optical activity[α]20/D −56.8°, c = 2 in H2O
Melting point183-185 °C (dec.)(lit.)
03 /Safety & handling
GHS hazard pictogram: Toxic (GHS06)
Toxic
Danger

Hazard statements

  • H301Toxic if swallowed
  • H331Toxic if inhaled

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P301IF SWALLOWED
  • P311Call a POISON CENTER or doctor
Protective equipmentEyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Transport (UN / ADR)UN 1544 6.1/PG 3
Water hazard class (WGK, DE)3
Hazard codes (EU)T
Risk statements (R)23/25
Safety statements (S)36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
134-63-4
MDL number
MFCD00082455
PubChem substance
24848513
Beilstein registry
3920196
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (–)-Lobeline hydrochloride used for?

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(–)-Lobeline hydrochloride is primarily used as a research chemical in neuroscience and pharmacology to study cholinergic pathways and neurotransmission. It also serves as a chiral building block in chemical synthesis.

What is the CAS number and chemical formula for (–)-Lobeline hydrochloride?

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The CAS number is 134-63-4 and the chemical formula is C22H27NO2 · HCl.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (–)-Lobeline hydrochloride with an assay of 98%. This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or any pharmacopoeia grade.

How should (–)-Lobeline hydrochloride be handled safely?

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(–)-Lobeline hydrochloride is classified as toxic if swallowed and toxic if inhaled (H301-H331). Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator cartridge. Ensure adequate ventilation. Refer to the Safety Data Sheet for full handling instructions.

Is (–)-Lobeline hydrochloride a controlled substance?

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The provided data does not indicate that (–)-Lobeline hydrochloride is a controlled substance. However, users are advised to consult local regulations.

How is (–)-Lobeline hydrochloride packed, shipped, and exported?

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This product is packed in accordance with international shipping regulations for hazardous materials (UN 1544, Class 6.1). Tech Serve Solutions is an experienced global exporter of fine chemicals.

How can I request a sample or quote for (–)-Lobeline hydrochloride?

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To request a sample or quote, please contact our sales team via the website or direct email, providing your contact details and the quantity required.

Need (−)-Lobeline hydrochloride in a specific grade or volume?