(−)-Isopinocampheylborane TMEDA complex
(−)-Isopinocampheylborane TMEDA complex (CAS: 67826-92-0; Formula: C13H27BN) is a chiral hydroboration reagent from Tech Serve Solutions. This amine-borane complex serves as a valuable tool in asymmetric synthesis. It is particularly noted for its use as a polarity-reversal catalyst in the kinetic resolution of racemic esters and ketones, enabling the selective transformation of chiral molecules.
- IUPAC
- (−)-N,N′-Bis(monoisopinocampheylborane)-N,N,N′,N′-tetramethylethylenediamine,(R)-Alpine-Boramine™
Chiral Hydroboration Reagent
This compound functions as a chiral hydroboration reagent, playing a key role in stereoselective synthetic transformations. Its specific structure facilitates the introduction of boron into organic molecules with defined stereochemistry.
Polarity-Reversal Catalyst
Utilised as a polarity-reversal catalyst, it is instrumental in the kinetic resolution of racemic esters and ketones. This application allows for the preferential reaction of one enantiomer over the other, leading to enantiomerically enriched products.
Asymmetric Synthesis
Within the field of asymmetric synthesis, this complex is employed to control the stereochemical outcome of reactions. Its chiral nature is essential for creating enantiomerically pure compounds required in pharmaceuticals and fine chemicals.
| Molecular weight | 208.17 |
|---|---|
| Empirical formula | C13H27BN |
| Application | Chiral hydroboration reagent.1,2This amine-borane complex has been used as a polarity-reversal catalyst for the kinetic resolution of racemic esters and ketones.3 |
| Melting point | 139-141 °C(lit.) |
Hazard statements
- H261In contact with water releases flammable gas
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P231Handle under inert gas
- P305IF IN EYES
- P422
| Protective equipment | dust mask type N95 (US), Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2813 4.3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 15-36/38 |
| Safety statements (S) | 26-36-43 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (–)-Isopinocampheylborane TMEDA complex used for?
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It is primarily used as a chiral hydroboration reagent and a polarity-reversal catalyst for the kinetic resolution of racemic esters and ketones in asymmetric synthesis.
What is the CAS number and formula for (–)-Isopinocampheylborane TMEDA complex?
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The CAS number is 67826-92-0 and the empirical formula is C13H27BN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. Specific assay and purity details are available on the Certificate of Analysis. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should (–)-Isopinocampheylborane TMEDA complex be handled safely?
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This compound is flammable and irritating. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator. Avoid contact with skin and eyes, and ensure adequate ventilation. It reacts with water, releasing flammable gas (H261).
Is this product available for international export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, and this product can be shipped internationally, subject to regulatory compliance.
How can I request a sample or quote?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number.
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