Guanosine 5′-[β-thio]diphosphate trilithium salt
Guanosine 5′-[β-thio]diphosphate trilithium salt (CAS 97952-36-8), with the formula C10H12Li3N5O10P2S and a molecular weight of 477.07 g/mol, is a stable analogue of GDP. This bioactive small molecule is primarily used in research settings for studying G protein function, cell signaling, and related biochemical pathways. Its thio-substitution offers increased resistance to enzymatic hydrolysis, making it a valuable tool in biochemical and cell biology research.
- IUPAC
- GDPβS trilithium salt,GDP-β-S-Li3,GDP-β-S
- Synonyms
- GDP-β-S trilithium saltGDPβS trilithium saltGDP-β-S-Li3GDP-β-S
![Guanosine 5′-[β-thio]diphosphate trilithium salt (C10H12Li3N5O10P2S) — chemical structure, CAS 97952-36-8; Life Science, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F97952-36-8.png&w=3840&q=75)
G Protein Research
Investigate the role of G proteins in signal transduction pathways. Guanosine 5′-[β-thio]diphosphate trilithium salt serves as a non-hydrolysable analogue to study GTP-binding protein activation and function.
Cell Signaling Studies
Explore intracellular communication mechanisms. This compound aids in understanding how cells respond to external stimuli by modulating signaling cascades involving G proteins.
Biochemical Assays
Utilised in in vitro assays to determine enzyme kinetics and inhibitor efficacy for targets involved in nucleotide binding and hydrolysis. Its stability allows for prolonged experimental conditions.
Neuroscience Research
Contribute to the understanding of neuronal signalling. The compound is relevant for studies concerning neurotransmitter receptors coupled to G proteins.
| Molecular weight | 477.07 |
|---|---|
| Empirical formula | C10H12Li3N5O10P2S |
| Assay | ≥85% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | H2O: soluble20 mg/mL (Solutions are very unstable; prepare immediately prior to use.) |
| Storage temperature | −20°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | dry ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Guanosine 5′-[β-thio]diphosphate trilithium salt used for?
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Guanosine 5′-[β-thio]diphosphate trilithium salt is used in research for studying G protein function, cell signaling pathways, biochemical assays, and neuroscience research due to its role as a stable analogue of GDP.
What is the CAS number and formula for Guanosine 5′-[β-thio]diphosphate trilithium salt?
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The CAS number is 97952-36-8 and the molecular formula is C10H12Li3N5O10P2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Guanosine 5′-[β-thio]diphosphate trilithium salt with an assay of ≥85% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Guanosine 5′-[β-thio]diphosphate trilithium salt be handled?
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This compound is a Warning hazard (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area. Avoid breathing dust and ensure good ventilation.
How is Guanosine 5′-[β-thio]diphosphate trilithium salt shipped?
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Guanosine 5′-[β-thio]diphosphate trilithium salt is shipped on dry ice to maintain appropriate storage conditions during transit.
How can I request a quote or sample?
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Please contact our sales team via the website or by phone to request a quote or inquire about sample availability for Guanosine 5′-[β-thio]diphosphate trilithium salt.
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