Guanosine 3′,5′-cyclic monophosphate
Guanosine 3′,5′-cyclic monophosphate (cGMP), CAS 7665-99-8, is a vital secondary messenger in eukaryotic cells with the molecular formula C10H12N5O7P and a molecular weight of 345.21 g/mol. This cyclic nucleotide plays a critical role in diverse cellular processes, including smooth muscle relaxation, neurotransmission, and photoreception. Tech Serve Solutions supplies high-purity cGMP for research applications in cell biology and signaling.
- IUPAC
- cGMP,cyclic GMP
- Synonyms
- cGMPcyclic GMPGuanosine-3',5'-monophosphate
Cellular Signaling Research
cGMP acts as a second messenger, mediating cellular responses to various extracellular signals. It is crucial for understanding signal transduction pathways in neuroscience and other biological systems.
Enzyme Activity Studies
This compound is a key substrate and regulator for various enzymes, particularly protein kinases like Protein Kinase G (PKG). Researchers use cGMP to investigate enzyme kinetics and regulatory mechanisms.
Vascular Biology Research
cGMP is a critical mediator of smooth muscle relaxation, influencing vascular tone and blood pressure. It is extensively studied in research related to cardiovascular health and disease.
Neuroscience Investigations
In the nervous system, cGMP is involved in processes such as synaptic plasticity and the regulation of neuronal excitability, making it a subject of interest in neurological research.
| Molecular weight | 345.21 |
|---|---|
| Empirical formula | C10H12N5O7P |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | 0.2 M NaHCO3: soluble50 mg/mL |
| Storage temperature | −20°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 22-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Guanosine 3′,5′-cyclic monophosphate used for?
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Guanosine 3′,5′-cyclic monophosphate (cGMP) is primarily used as a research tool in cell biology, cell signaling, neuroscience, and molecular biology to study cellular processes and enzyme mechanisms.
What are the CAS number and formula for Guanosine 3′,5′-cyclic monophosphate?
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The CAS number for Guanosine 3′,5′-cyclic monophosphate is 7665-99-8. Its empirical formula is C10H12N5O7P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Guanosine 3′,5′-cyclic monophosphate with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Guanosine 3′,5′-cyclic monophosphate be handled?
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Handle with appropriate personal protective equipment, including a dust mask (N95 type), eyeshields, and gloves. Avoid inhalation of dust and contact with skin and eyes. Ensure adequate ventilation. This compound is classified as an irritant.
How is Guanosine 3′,5′-cyclic monophosphate packed, shipped, and exported?
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Guanosine 3′,5′-cyclic monophosphate is typically supplied as a white powder and stored at -20°C. We are experienced in exporting fine chemicals globally, ensuring compliance with all relevant shipping regulations.
How can I request a sample or quote for Guanosine 3′,5′-cyclic monophosphate?
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To request a sample or a quote for Guanosine 3′,5′-cyclic monophosphate, please contact our sales team through the website or by phone. We will be happy to assist you.
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