Dichlorodiphenoxymethane
Dichlorodiphenoxymethane (CAS: 4885-03-4), with the linear formula (C₆H₅O)₂CCl₂, is a specialised organic chemical compound with a molecular weight of 269.12 g/mol. It serves as a key building block in organic synthesis, particularly in cyclocondensation reactions. Its applications extend to the preparation of specific pharmaceutical intermediates, notably those explored for treating ocular hypertension. Tech Serve Solutions offers this compound for research and chemical synthesis purposes.
- IUPAC
- Phosgene diphenyl acetal
Cyclocondensation Reactions
Dichlorodiphenoxymethane acts as a valuable reagent in cyclocondensation reactions involving aminophenols and amines. This application is crucial for synthesising complex heterocyclic structures used in further chemical development.
Ocular Hypertension Therapeutics
This compound is employed in the preparation of LIM-Kinase 2 inhibitors. These inhibitors are investigated for their therapeutic potential in managing ocular hypertension, contributing to advancements in ophthalmic drug discovery.
Organic Synthesis Intermediate
As a versatile building block, Dichlorodiphenoxymethane facilitates the synthesis of various organic molecules. Its specific structure allows for its incorporation into diverse chemical pathways within research and development settings.
| Molecular weight | 269.12 |
|---|---|
| Linear formula | (C6H5O)2CCl2 |
| Application | Reactant for:• Cyclocondensation of aminophenols and amines1• Preparation of LIM-Kinase 2 inhibitors for the treatment of ocular hypertension2 |
| Melting point | 39-44 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 1759 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dichlorodiphenoxymethane primarily used for?
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Dichlorodiphenoxymethane is primarily used as a reagent in cyclocondensation reactions and in the preparation of LIM-Kinase 2 inhibitors for potential ocular hypertension treatments. It also serves as a general building block in organic synthesis.
What is the CAS number and chemical formula for Dichlorodiphenoxymethane?
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The CAS number for Dichlorodiphenoxymethane is 4885-03-4, and its linear chemical formula is (C₆H₅O)₂CCl₂.
What grade and purity does Tech Serve Solutions supply for Dichlorodiphenoxymethane?
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Tech Serve Solutions supplies Dichlorodiphenoxymethane typically as a research or technical grade chemical. We do not represent it as USP, BP, or EP grade unless explicitly stated in the product specifications. Please refer to the product specification sheet for lot-specific details.
How should Dichlorodiphenoxymethane be handled safely?
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Dichlorodiphenoxymethane is classified as corrosive (H314) and requires careful handling. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection (e.g., N100 or P3 rated filters), must be used. Handle in a well-ventilated area and avoid contact with skin, eyes, and clothing. Refer to the safety data sheet for comprehensive handling instructions.
Is Dichlorodiphenoxymethane a controlled substance?
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Based on the provided data, Dichlorodiphenoxymethane is not listed as a controlled substance. However, users should always verify compliance with local and international regulations.
How is Dichlorodiphenoxymethane packaged and shipped?
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Dichlorodiphenoxymethane is shipped according to UN 1759, Class 8, Packing Group II regulations for corrosive materials. Packaging will be appropriate for its hazardous nature to ensure safe transport and export.
How can I request a quote or sample of Dichlorodiphenoxymethane?
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To request a quote or a sample of Dichlorodiphenoxymethane, please contact the Tech Serve Solutions sales department via our website or direct contact information, specifying the product CAS number (4885-03-4) and the quantity required.
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