Dichlorodiisopropylsilane
Dichlorodiisopropylsilane (CAS 7751-38-4), with the chemical formula C6H14Cl2Si and a molecular weight of 185.17 g/mol, is a silicon-based organic compound. It is primarily employed as a reagent in chemical synthesis. Its properties make it useful in protection and derivatization strategies within organic chemistry laboratories. Tech Serve Solutions offers this compound for research and development purposes.
- IUPAC
- Diisopropyldichlorosilane
- Synonyms
- Diisopropyldichlorosilane

Protecting Group Reagent
Dichlorodiisopropylsilane can be utilised to introduce isopropylsilyl protecting groups onto hydroxyl functionalities in organic synthesis. This allows for selective modification of complex molecules by temporarily masking reactive sites.
Derivatization Agent
This silane serves as a derivatizing agent in analytical chemistry, enabling the transformation of analytes into more volatile or detectable forms for techniques such as gas chromatography.
Synthesis of Organosilicon Compounds
It acts as a building block in the synthesis of more complex organosilicon compounds, contributing its diisopropylsilyl moiety to the target structure.
| Molecular weight | 185.17 |
|---|---|
| Empirical formula | C6H14Cl2Si |
| Assay | ≥97.0% (GC) |
| Boiling point | 66 °C/27 mmHg(lit.) |
| Density | 1.026 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.444 |


Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 43 °C / 109.4 °F |
| Transport (UN / ADR) | UN 2986 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34 |
| Safety statements (S) | 28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dichlorodiisopropylsilane used for?
+
Dichlorodiisopropylsilane is used as a reagent in chemical synthesis, particularly for introducing isopropylsilyl protecting groups and in the derivatization of compounds for analysis.
What is the CAS number and formula for Dichlorodiisopropylsilane?
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The CAS number is 7751-38-4 and the chemical formula is C6H14Cl2Si.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dichlorodiisopropylsilane with an assay of ≥97.0% (GC). This is a technical/research grade; TSS does not represent it as USP/BP/EP.
How should Dichlorodiisopropylsilane be handled safely?
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Dichlorodiisopropylsilane is flammable and causes severe skin burns and eye damage. Handle with extreme care, wearing appropriate personal protective equipment including gloves, eye protection, and respiratory protection. Ensure adequate ventilation and avoid ignition sources.
How is this chemical shipped and exported?
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This chemical is classified as UN 2986, hazard class 3(8), packing group II, and is shipped and exported according to international regulations for hazardous materials.
How can I request a sample or quote?
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To request a sample or a quotation for Dichlorodiisopropylsilane, please contact our sales team through the TSS website or by phone.
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