1-Methylhydantoin
1-Methylhydantoin (CAS 616-04-6; C4H6N2O2; MW 114.10) is a heterocyclic organic compound used as a building block in chemical synthesis. Its primary applications lie in its role as a reactant for organocatalytic reactions and in the synthesis of various biologically active molecules, including selective angiotensin II AT2 receptor agonists and allosteric glucokinase activators. This compound is supplied by TSS with an assay of 97%.
- IUPAC
- 1-Methylimidazolidine-2,4-dione,Dioxy-creatinine,NSC 80560
- Synonyms
- 1-Methylimidazolidine-2,4-dioneDioxy-creatinineNSC 80560
Organocatalytic Reactions
Serves as a key reactant in organocatalytic tandem three-component reactions involving aldehydes, alkyl vinyl ketones, and amides.
Angiotensin II AT2 Receptor Agonists
Utilised in the synthesis of selective angiotensin II AT2 receptor agonists, designed with reduced CYP 450 inhibition.
Glucokinase Activators
A precursor in the development of allosteric glucokinase activators, which play a role in glucose metabolism regulation.
Hydantoin Derivatives
Employed in the synthesis of hydantoin derivatives exhibiting antiproliferative activity.
Thiohydantoin Synthesis
Acts as a reactant in the preparation of thiohydantoin compounds.
P2X7 Receptor Antagonists
Used in the synthetic pathways leading to P2X7 receptor antagonists.
| Molecular weight | 114.10 |
|---|---|
| Empirical formula | C4H6N2O2 |
| Assay | 97% |
| Application | Reactant for organocatalytic tandem three component reactions of aldehyde, alkyl vinyl ketone, and amide1Reactant for synthesis of:• Selective angiotensin II AT2 receptor agonists with reduced CYP 450 inhibition2• Allosteric glucokinase activators3• Hydantoin derivatives with antiproliferative activity4• Thiohydantoins5• P2X7 receptor antagonists6 |
| Melting point | 156-157 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Methylhydantoin used for?
+
1-Methylhydantoin is used as a reactant in organocatalytic tandem three-component reactions and in the synthesis of various compounds, including selective angiotensin II AT2 receptor agonists, allosteric glucokinase activators, hydantoin derivatives with antiproliferative activity, thiohydantoins, and P2X7 receptor antagonists.
What is the CAS number and formula for 1-Methylhydantoin?
+
The CAS number for 1-Methylhydantoin is 616-04-6, and its empirical formula is C4H6N2O2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 1-Methylhydantoin with an assay of 97%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
What are the safety and handling requirements for 1-Methylhydantoin?
+
Handling 1-Methylhydantoin requires personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with a WGK Germany rating of 3.
How is 1-Methylhydantoin packed and shipped?
+
1-Methylhydantoin is packed and shipped according to industry best practices for chemical compounds, ensuring safe transit for domestic and international export.
How can I request a sample or quote for 1-Methylhydantoin?
+
To request a sample or a quote for 1-Methylhydantoin, please contact our sales team through the website or by phone.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis