1-Methylhomopiperazine
1-Methylhomopiperazine (CAS 4318-37-0), with the molecular formula C6H14N2 and a molecular weight of 114.19 g/mol, is a heterocyclic organic compound. It is a valuable building block in organic synthesis, particularly for the construction of complex molecules. This chemical serves as a key intermediate in the development of novel compounds with potential pharmacological applications and in the synthesis of coordination complexes.
- IUPAC
- Hexahydro-1-methyl-1H-1,4-diazepine

Synthesis of Benzimidazole Derivatives
1-Methylhomopiperazine has been employed in the synthesis of new benzimidazole derivatives, which are investigated for their pharmacological activities. This highlights its utility in medicinal chemistry research and drug discovery.
Coordination Chemistry
The compound has been used in the preparation of platinum(II) substituted disulfide complexes. This indicates its role as a ligand or precursor in inorganic and organometallic chemistry.
Heterocyclic Building Block
As a piperazine derivative, 1-Methylhomopiperazine functions as a versatile heterocyclic building block in various chemical synthesis pathways. Its structure allows for diverse functionalisation.
| Molecular weight | 114.19 |
|---|---|
| Empirical formula | C6H14N2 |
| Assay | 97% |
| Boiling point | 74-75 °C/35 mmHg(lit.) |
| Density | 0.918 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.477(lit.) |
| Application | 1-Methylhomopiperazine was used in the synthesis of:• novel benzimidazole derivatives having pharmacological activities1• platinum(II) substituted disulfide complexes2 |



Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 45 °C / 113 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-22-34 |
| Safety statements (S) | 16-26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Methylhomopiperazine used for?
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1-Methylhomopiperazine is used as a building block in chemical synthesis, notably for preparing novel benzimidazole derivatives with pharmacological activities and platinum(II) substituted disulfide complexes.
What are the CAS number and formula for 1-Methylhomopiperazine?
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The CAS number for 1-Methylhomopiperazine is 4318-37-0, and its molecular formula is C6H14N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Methylhomopiperazine with a purity of 97% (Assay). This product is intended for laboratory and research use and is not represented as USP, BP, or EP grade.
What are the safety considerations for handling 1-Methylhomopiperazine?
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1-Methylhomopiperazine is a dangerous substance classified with H226 (Flammable liquid and vapour), H302 (Harmful if swallowed), and H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including gloves, goggles, and respiratory protection, must be used, and handling should occur in a well-ventilated area.
Is 1-Methylhomopiperazine a controlled substance?
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The provided data does not indicate that 1-Methylhomopiperazine is a controlled substance.
How is 1-Methylhomopiperazine packed and shipped?
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1-Methylhomopiperazine is shipped as UN 2920, Hazard Class 3 (8), Packing Group II, indicating it is a flammable and corrosive liquid. TSS exports chemicals globally, adhering to all relevant transport regulations.
How can I request a quote or sample?
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To request a quote or sample of 1-Methylhomopiperazine, please contact the Tech Serve Solutions sales team through our website or direct contact details.
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