Methysergide maleate salt
Methysergide maleate salt (CAS: 129-49-7), with the molecular formula C21H27N3O2 · C4H4O4 and a molecular weight of 469.53, is supplied by TSS as a white to off-white solid. This compound acts as a serotonin receptor antagonist. It is recognised for its utility in neurochemical research, particularly concerning serotonin pathways and their involvement in neurological functions and disorders. Its applications span various areas of biochemical and pharmacological investigation.
Serotonin Receptor Antagonism Research
Methysergide maleate salt serves as a valuable tool for investigating the function of serotonin receptors (e.g., HTR1A, HTR1B, HTR2A) in cellular and animal models. Researchers utilise its antagonistic properties to probe the roles of these receptors in neurotransmission and physiological processes.
Neuroscience Drug Discovery
As a bioactive molecule targeting neurotransmission, this compound is employed in the early stages of drug discovery for neurological disorders. It aids in understanding receptor-ligand interactions and identifying potential therapeutic targets within the central nervous system.
Biochemical Assays
The solubility of methysergide maleate salt in DMSO and water allows for its use in various in vitro biochemical assays. It is suitable for cell-based studies investigating cellular responses mediated by serotonin receptor activation or blockade.
| Molecular weight | 469.53 |
|---|---|
| Empirical formula | C21H27N3O2 · C4H4O4 |
| Form | solid |
| Colour | white to off-white |
| Solubility | DMSO: >10 mg/mLH2O: soluble2 mg/mL |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methysergide maleate salt used for?
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Methysergide maleate salt is primarily used in research for investigating serotonin receptor antagonism, particularly within neuroscience and cell signalling studies.
What are the CAS number and formula for Methysergide maleate salt?
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The CAS number is 129-49-7, and the empirical formula (Hill notation) is C21H27N3O2 · C4H4O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research-grade chemical. The specific purity and assay are detailed in the product specifications; TSS does not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should Methysergide maleate salt be handled safely?
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Methysergide maleate salt is classified as toxic if swallowed (H301) and requires stringent handling procedures. Use appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges. Ensure adequate ventilation and avoid ingestion.
Is Methysergide maleate salt a controlled substance?
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The provided data does not indicate that Methysergide maleate salt is a controlled substance. However, users should always verify local regulations.
How is Methysergide maleate salt shipped and exported?
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This chemical is shipped and exported in compliance with international transport regulations for hazardous materials, identified under UN 2811, Hazard Class 6.1, Packing Group III.
How can I request a sample or quote for Methysergide maleate salt?
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To request a sample or a quotation for Methysergide maleate salt, please contact our sales department through the website or by phone.
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