Methyl-β-cyclodextrin
Methyl-β-cyclodextrin (CAS 128446-36-6) is a synthetic cyclic oligosaccharide derived from glucose. It possesses a unique toroidal structure with a hydrophilic exterior and a hydrophobic interior cavity, enabling it to form inclusion complexes with various molecules. This property makes it valuable for modifying solubility, stability, and bioavailability. It is frequently employed in biochemical research, pharmaceutical formulation, and as a complexing agent in analytical chemistry.
Solubility Enhancement
Methyl-β-cyclodextrin can encapsulate poorly soluble drugs within its hydrophobic cavity, significantly increasing their aqueous solubility and improving bioavailability in pharmaceutical formulations.
Stabilisation of Active Compounds
It protects sensitive molecules, such as fragrances or active pharmaceutical ingredients, from degradation caused by light, oxidation, or heat by forming stable inclusion complexes.
Biochemical Research
This compound is used in cell culture applications and as a tool to study protein folding and enzyme kinetics due to its ability to interact with biological molecules.
Analytical Chemistry
Methyl-β-cyclodextrin serves as a stationary phase modifier in chromatography and as a complexing agent in electrochemistry, aiding in the separation and detection of analytes.
| Solubility | H2O: soluble50 mg/mL |
|---|---|
| Suitability | suitable for cell culture |
| Melting point | 180-182 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 187 °C / 368.6 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl-β-cyclodextrin used for?
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Methyl-β-cyclodextrin is used for solubility enhancement, stabilisation of active compounds, in biochemical research, and in analytical chemistry.
What is the CAS number and formula for Methyl-β-cyclodextrin?
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The CAS number for Methyl-β-cyclodextrin is 128446-36-6. The molecular formula is not provided in the data.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl-β-cyclodextrin suitable for cell culture and with a solubility of 50 mg/mL in water. It is not represented as USP, BP, or EP grade.
What are the safety and handling considerations for Methyl-β-cyclodextrin?
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When handling Methyl-β-cyclodextrin, appropriate personal protective equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter should be used. It has a flash point of 187 °C (368.6 °F).
How is Methyl-β-cyclodextrin packed and shipped?
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Tech Serve Solutions expertly packs and exports Methyl-β-cyclodextrin globally, adhering to all necessary regulations for safe transport.
How can I request a sample or quote for Methyl-β-cyclodextrin?
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To request a sample or obtain a quote for Methyl-β-cyclodextrin, please contact our sales team via the website or by phone.
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