2,5-Thiophenediylbisboronic acid
2,5-Thiophenediylbisboronic acid (CAS: 26076-46-0) is an organoboron compound with the empirical formula C4H6B2O4S and a molecular weight of 171.78 g/mol. It is characterised by its thiophene core substituted with two boronic acid groups. This compound serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions for the formation of carbon-carbon bonds, and is employed in the development of novel materials and pharmaceutical intermediates.
- IUPAC
- 2,5-Thiophenediboronic acid
- Synonyms
- C4H6B2O4S2,5-Thiophenediboronic acid

Organic Synthesis Intermediate
Utilised as a difunctional building block in Suzuki-Miyaura cross-coupling reactions to synthesise complex organic molecules. It enables the introduction of thiophene moieties into various molecular architectures.
Materials Science
Incorporated into the synthesis of conjugated polymers and organic electronic materials. The thiophene unit contributes to desirable electronic and optical properties.
Pharmaceutical Research
Acts as a key intermediate in the discovery and development of new pharmaceutical agents, where the thiophene scaffold is a common feature in bioactive compounds.
| Molecular weight | 171.78 |
|---|---|
| Empirical formula | C4H6B2O4S |
| Assay | ≥95.0% |
| Melting point | 250 °C (dec.)(lit.) |

Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Thiophenediylbisboronic acid used for?
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2,5-Thiophenediylbisboronic acid is primarily used as a building block in organic synthesis, particularly for cross-coupling reactions like the Suzuki-Miyaura coupling, and in materials science for developing conjugated polymers and organic electronics.
What is the CAS number and formula for 2,5-Thiophenediylbisboronic acid?
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The CAS number is 26076-46-0 and the empirical formula is C4H6B2O4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,5-Thiophenediylbisboronic acid with an assay of ≥95.0%. This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.
How should 2,5-Thiophenediylbisboronic acid be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. This compound is a Warning hazard (H319), causing serious eye irritation. Ensure good ventilation and avoid dust formation. Refer to the Safety Data Sheet for full details.
Can Tech Serve Solutions export 2,5-Thiophenediylbisboronic acid?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2,5-Thiophenediylbisboronic acid, facilitating international delivery.
How can I request a quote or sample for 2,5-Thiophenediylbisboronic acid?
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Please contact our sales team or use the online enquiry form on our website to request a quote or sample for 2,5-Thiophenediylbisboronic acid.
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