2,6-Difluorophenyl isocyanate
2,6-Difluorophenyl isocyanate (CAS 65295-69-4) is a fluorinated organic building block with the molecular formula F2C6H3NCO and a molecular weight of 155.10 g/mol. This compound serves as a valuable intermediate in organic synthesis, particularly for introducing the 2,6-difluorophenyl moiety into various molecular structures. Its reactive isocyanate group enables diverse chemical transformations, making it essential for research and development in pharmaceuticals and materials science.
- Synonyms
- F2C6H3NCO
Pharmaceutical Intermediate
Utilised in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs). The 2,6-difluorophenyl group can impart desirable pharmacokinetic and pharmacodynamic properties to drug molecules.
Agrochemical Synthesis
Employed as a building block for the creation of advanced agrochemicals, including herbicides, insecticides, and fungicides. The incorporation of fluorine atoms can enhance biological activity and stability.
Materials Science Research
Serves as a precursor for developing advanced materials with specific properties. Its reactive nature allows for incorporation into polymers and other functional materials.
Organic Synthesis Reagent
A versatile reagent in organic chemistry for reactions such as addition, cyclisation, and condensation, facilitating the construction of complex organic molecules.
| Molecular weight | 155.10 |
|---|---|
| Linear formula | F2C6H3NCO |
| Assay | 97% |
| Boiling point | 60 °C/10 mmHg(lit.) |
| Refractive index | n20/D 1.4928(lit.) |
| Storage temperature | 2-8°C |
| Melting point | 22-25 °C(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 58 °C / 136.4 °F |
| Transport (UN / ADR) | UN 2930 6.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 23-26-28-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,6-Difluorophenyl isocyanate used for?
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2,6-Difluorophenyl isocyanate is primarily used as an intermediate in pharmaceutical and agrochemical synthesis, and in materials science research, due to its ability to introduce the 2,6-difluorophenyl group into target molecules.
What is the CAS number and chemical formula for 2,6-Difluorophenyl isocyanate?
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The CAS number is 65295-69-4 and the chemical formula is F2C6H3NCO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,6-Difluorophenyl isocyanate with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for 2,6-Difluorophenyl isocyanate?
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This compound is classified as Warning with hazards including flammability (H226), and is harmful if swallowed, in contact with skin, or if inhaled (H302, H312, H332). It also causes skin irritation (H315) and serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, should be used. Ensure adequate ventilation and avoid ignition sources.
How is 2,6-Difluorophenyl isocyanate shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and reagents. We handle shipping and export in compliance with all relevant international regulations.
How can I request a quote or sample for 2,6-Difluorophenyl isocyanate?
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Please contact our sales team directly via the website or phone to request a quote or a sample of 2,6-Difluorophenyl isocyanate.
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