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2,3,4-Trifluorobenzoyl chloride

CAS 157373-08-5F3C6H2COClChemical Synthesis

2,3,4-Trifluorobenzoyl chloride (CAS: 157373-08-5; F3C6H2COCl) is a fluorinated aromatic acid halide. It serves as a versatile building block in organic synthesis. This compound is characterised by its reactive acyl chloride group, making it valuable for introducing the 2,3,4-trifluorobenzoyl moiety into various organic molecules. It is primarily utilised in the research and development sectors for the synthesis of complex organic compounds and speciality chemicals.

Synonyms
157373-08-5F3C6H2COCl
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2,3,4-Trifluorobenzoyl chloride (F3C6H2COCl) — chemical structure, CAS 157373-08-5; Chemistry, fine chemical supplied by Tech Serve Solutions
Acid HalidesBuilding BlocksCarbonyl CompoundsChemical SynthesisOrganic Building Blocks
01 /Applications

Organic Synthesis Intermediate

Serves as a key intermediate in the synthesis of fluorinated organic compounds. Its reactive nature allows for facile acylation reactions, enabling the construction of more complex molecular architectures.

Pharmaceutical Research

Utilised in the development of novel pharmaceutical agents where the trifluorobenzoyl group may impart specific biological or pharmacokinetic properties.

Agrochemical Development

A potential building block for the synthesis of new agrochemicals, contributing to the development of crop protection agents.

Materials Science

Can be employed in the synthesis of specialised polymers or materials where its unique structural features are advantageous.

02 /Properties
Molecular weight194.54
Linear formulaF3C6H2COCl
Assay98%
Boiling point143-144 °C/130 mmHg(lit.)
Density1.522 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.497(lit.)
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H314Causes severe skin burns and eye damage
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point93 °C / 199.4 °F
Transport (UN / ADR)UN 3265 8 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)34-36/37
Safety statements (S)23-26-27-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
157373-08-5
MDL number
MFCD00075078
PubChem substance
24860383
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2,3,4-Trifluorobenzoyl chloride used for?

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2,3,4-Trifluorobenzoyl chloride (CAS: 157373-08-5) is used as a building block and intermediate in organic synthesis, particularly in the research and development of pharmaceuticals, agrochemicals, and speciality materials.

What is the CAS number and formula for 2,3,4-Trifluorobenzoyl chloride?

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The CAS number is 157373-08-5, and the linear formula is F3C6H2COCl. The molecular weight is 194.54 g/mol.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2,3,4-Trifluorobenzoyl chloride with an assay of 98%. This is a technical/research grade chemical and is not represented as USP, BP, or EP grade.

What are the primary safety hazards associated with 2,3,4-Trifluorobenzoyl chloride?

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This compound is classified as Danger, with hazards including causing severe skin burns and eye damage (H314) and potentially causing respiratory irritation (H335). Appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, is essential during handling. Always consult the Safety Data Sheet (SDS) before use.

How is 2,3,4-Trifluorobenzoyl chloride packed and shipped?

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As a specialist global supplier and exporter, Tech Serve Solutions ensures that 2,3,4-Trifluorobenzoyl chloride is packed and shipped in compliance with all relevant regulations for hazardous materials. International shipments adhere to standards such as UN 3265, Class 8, Packing Group II.

How can I request a quote or sample of 2,3,4-Trifluorobenzoyl chloride?

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To request a quote or sample, please contact our sales department via the website or direct email. Our team will be happy to assist you with your specific requirements.

Need 2,3,4-Trifluorobenzoyl chloride in a specific grade or volume?