2,3,4-Trifluorobenzoyl chloride
2,3,4-Trifluorobenzoyl chloride (CAS: 157373-08-5; F3C6H2COCl) is a fluorinated aromatic acid halide. It serves as a versatile building block in organic synthesis. This compound is characterised by its reactive acyl chloride group, making it valuable for introducing the 2,3,4-trifluorobenzoyl moiety into various organic molecules. It is primarily utilised in the research and development sectors for the synthesis of complex organic compounds and speciality chemicals.
- Synonyms
- 157373-08-5F3C6H2COCl

Organic Synthesis Intermediate
Serves as a key intermediate in the synthesis of fluorinated organic compounds. Its reactive nature allows for facile acylation reactions, enabling the construction of more complex molecular architectures.
Pharmaceutical Research
Utilised in the development of novel pharmaceutical agents where the trifluorobenzoyl group may impart specific biological or pharmacokinetic properties.
Agrochemical Development
A potential building block for the synthesis of new agrochemicals, contributing to the development of crop protection agents.
Materials Science
Can be employed in the synthesis of specialised polymers or materials where its unique structural features are advantageous.
| Molecular weight | 194.54 |
|---|---|
| Linear formula | F3C6H2COCl |
| Assay | 98% |
| Boiling point | 143-144 °C/130 mmHg(lit.) |
| Density | 1.522 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.497(lit.) |


Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 93 °C / 199.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-36/37 |
| Safety statements (S) | 23-26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3,4-Trifluorobenzoyl chloride used for?
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2,3,4-Trifluorobenzoyl chloride (CAS: 157373-08-5) is used as a building block and intermediate in organic synthesis, particularly in the research and development of pharmaceuticals, agrochemicals, and speciality materials.
What is the CAS number and formula for 2,3,4-Trifluorobenzoyl chloride?
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The CAS number is 157373-08-5, and the linear formula is F3C6H2COCl. The molecular weight is 194.54 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,3,4-Trifluorobenzoyl chloride with an assay of 98%. This is a technical/research grade chemical and is not represented as USP, BP, or EP grade.
What are the primary safety hazards associated with 2,3,4-Trifluorobenzoyl chloride?
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This compound is classified as Danger, with hazards including causing severe skin burns and eye damage (H314) and potentially causing respiratory irritation (H335). Appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, is essential during handling. Always consult the Safety Data Sheet (SDS) before use.
How is 2,3,4-Trifluorobenzoyl chloride packed and shipped?
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As a specialist global supplier and exporter, Tech Serve Solutions ensures that 2,3,4-Trifluorobenzoyl chloride is packed and shipped in compliance with all relevant regulations for hazardous materials. International shipments adhere to standards such as UN 3265, Class 8, Packing Group II.
How can I request a quote or sample of 2,3,4-Trifluorobenzoyl chloride?
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To request a quote or sample, please contact our sales department via the website or direct email. Our team will be happy to assist you with your specific requirements.
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