2,3,4-Trifluorophenol
2,3,4-Trifluorophenol (CAS: 2822-41-5), a fluorinated aromatic compound with the molecular formula F3C6H2OH and a molecular weight of 148.08 g/mol. This phenol derivative is characterised by its three fluorine substituents, making it a valuable intermediate in organic synthesis. It is frequently employed as a building block in the development of complex molecules within the pharmaceutical and agrochemical industries, leveraging its unique electronic and steric properties.
- Synonyms
- 2822-41-5F3C6H2OH
Pharmaceutical Intermediates
Utilised as a key building block in the synthesis of active pharmaceutical ingredients (APIs). The trifluorophenol moiety can be incorporated into drug candidates to modulate properties such as lipophilicity, metabolic stability, and receptor binding affinity.
Agrochemical Synthesis
Serves as a precursor for the development of novel pesticides, herbicides, and fungicides. The presence of fluorine atoms can enhance the efficacy and environmental profile of agrochemical products.
Materials Science Research
Explored in the synthesis of advanced materials, such as liquid crystals or specialty polymers, where its specific electronic and structural attributes are beneficial for performance.
Organic Synthesis Reagent
Employed as a versatile reagent in various organic transformations due to the activating and directing effects of the hydroxyl and fluorine groups on the aromatic ring.
| Molecular weight | 148.08 |
|---|---|
| Linear formula | F3C6H2OH |
| Assay | 97% |
| Boiling point | 69 °C/43 mmHg(lit.) |
| Density | 1.46 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.465(lit.) |
| Melting point | 30-34 °C(lit.) |
Hazard statements
- H228Flammable solid
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 59 °C / 138.2 °F |
| Transport (UN / ADR) | UN 1325 4.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3,4-Trifluorophenol used for?
+
2,3,4-Trifluorophenol is primarily used as a building block in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. It is a valuable intermediate in organic synthesis.
What is the CAS number and molecular formula for 2,3,4-Trifluorophenol?
+
The CAS number for 2,3,4-Trifluorophenol is 2822-41-5, and its linear molecular formula is F3C6H2OH.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2,3,4-Trifluorophenol with a minimum purity of 97% (assay). This product is typically supplied for research and development purposes and is not represented as USP, BP, or EP grade.
How should 2,3,4-Trifluorophenol be handled safely?
+
2,3,4-Trifluorophenol is a flammable solid and is harmful if swallowed, in contact with skin, or if inhaled. It also causes skin irritation, serious eye irritation, and respiratory irritation. Appropriate personal protective equipment, including a dust mask (N95 US), eyeshields, and gloves, should be worn. Handle in a well-ventilated area away from ignition sources.
Is 2,3,4-Trifluorophenol shipped internationally?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2,3,4-Trifluorophenol. We handle all necessary export documentation and comply with international shipping regulations for hazardous materials such as UN 1325.
How can I request a quote or sample for 2,3,4-Trifluorophenol?
+
To request a quote or a sample of 2,3,4-Trifluorophenol, please contact our sales department through the website or by phone. Please specify the quantity and your intended use.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis