2,3,4-Trifluorophenylboronic acid
2,3,4-Trifluorophenylboronic acid (CAS 226396-32-3) is a fluorinated aryl boronic acid with the linear formula F3C6H2B(OH)2 and a molar mass of 175.90 g/mol. This compound serves as a key building block in organic synthesis. Its primary application lies in its role as a reactant for the preparation of arylated carbonyl compounds through conjugate addition reactions, offering precise functionalisation in complex molecule construction.
- IUPAC
- 4,5,6-Trifluorophenylboronic acid
- Synonyms
- 226396-32-3F3C6H2B(OH)24,5,6-Trifluorophenylboronic acid
Preparation of Arylated Carbonyl Compounds
2,3,4-Trifluorophenylboronic acid acts as a valuable reactant in conjugate addition reactions. This process facilitates the efficient synthesis of arylated carbonyl compounds, which are important structural motifs in various organic molecules.
Fluorinated Building Block
As a trifluorinated aryl boronic acid, this compound is a useful synthon for introducing fluorine atoms into organic structures. Fluorine substitution can significantly alter the physical, chemical, and biological properties of molecules, making it relevant in pharmaceutical and materials science research.
Organometallic Synthesis
This compound belongs to the class of organometallic reagents. Aryl boronic acids are versatile intermediates in various cross-coupling reactions, enabling the formation of carbon-carbon bonds.
| Molecular weight | 175.90 |
|---|---|
| Linear formula | F3C6H2B(OH)2 |
| Assay | ≥95% |
| Application | Reactant for:• Preparation of arylated carbonyl compounds via conjugate addition reaction1 |
| Melting point | 229-235 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3,4-Trifluorophenylboronic acid used for?
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2,3,4-Trifluorophenylboronic acid is used as a reactant for the preparation of arylated carbonyl compounds via conjugate addition reactions.
What are the CAS number and formula for 2,3,4-Trifluorophenylboronic acid?
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The CAS number is 226396-32-3, and the linear formula is F3C6H2B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,3,4-Trifluorophenylboronic acid with an assay of ≥95%. This product is supplied for research and development purposes and is not intended for USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling requirements for 2,3,4-Trifluorophenylboronic acid?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound has a WGK rating of 3 in Germany, indicating it is hazardous to water.
How is 2,3,4-Trifluorophenylboronic acid packed, shipped, and exported?
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Tech Serve Solutions expertly packs, ships, and exports fine chemicals globally, adhering to all relevant regulations to ensure safe and compliant delivery.
How can I request a sample or a quote for 2,3,4-Trifluorophenylboronic acid?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number (226396-32-3).
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