4-Hydroxy-3-nitrobenzaldehyde
4-Hydroxy-3-nitrobenzaldehyde (CAS: 3011-34-5; Formula: HOC6H3(NO2)CHO; MW: 167.12) is a specialized organic compound characterised by its aldehyde and nitro functional groups, along with a hydroxyl substituent on the benzene ring. Utilised as a key intermediate and building block in organic synthesis, it finds application in the preparation of more complex molecules. Its specific chemical structure makes it valuable for research and development in pharmaceutical and materials science sectors.
Synthesis of Cinnamic Acid Derivatives
4-Hydroxy-3-nitrobenzaldehyde serves as a precursor in the synthesis of substituted cinnamic acids. For instance, it has been used in the preparation of 4-hydroxy-3-nitrocinnamic acid.
Formation of Solvated Benzohydrazone Derivatives
The compound is employed in the creation of various benzohydrazone derivatives. An example includes the synthesis of solvated N'-(4-hydroxy-3-nitrobenzylidene)-3-methylbenzohydrazide-methanol-water complexes.
Organic Building Block
As an aldehyde and a functionalised aromatic compound, it acts as a versatile building block in diverse organic synthesis pathways, enabling the construction of complex molecular architectures.
| Molecular weight | 167.12 |
|---|---|
| Linear formula | HOC6H3(NO2)CHO |
| Assay | 97% |
| Application | 4-Hydroxy-3-nitrobenzaldehyde was used in the synthesis of:• 4-hydroxy-3-nitrocinnamic acid1 • solvated benzohydrazone derivatives: N′-(4-hydroxy-3-nitrobenzylidene)-3-methylbenzohydrazide-methanol-water2 |
| Melting point | 140-142 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Hydroxy-3-nitrobenzaldehyde used for?
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4-Hydroxy-3-nitrobenzaldehyde is primarily used as a building block in organic synthesis for creating more complex molecules, such as substituted cinnamic acids and benzohydrazone derivatives.
What are the CAS number and formula for 4-Hydroxy-3-nitrobenzaldehyde?
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The CAS number for 4-Hydroxy-3-nitrobenzaldehyde is 3011-34-5, and its linear formula is HOC6H3(NO2)CHO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Hydroxy-3-nitrobenzaldehyde with an assay of 97%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the main hazards associated with 4-Hydroxy-3-nitrobenzaldehyde?
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According to the GHS classification, 4-Hydroxy-3-nitrobenzaldehyde is a warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used when handling this chemical.
How is 4-Hydroxy-3-nitrobenzaldehyde packed and shipped?
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Tech Serve Solutions reliably packs and ships fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to all relevant safety and export regulations.
How can I request a sample or quote for 4-Hydroxy-3-nitrobenzaldehyde?
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To request a sample or a quotation for 4-Hydroxy-3-nitrobenzaldehyde, please contact our sales team through the website or by phone.
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