3-Fluoro-2-methylphenylmagnesium chloride solution
3-Fluoro-2-methylphenylmagnesium chloride solution (CAS: 480424-74-6) is a valuable Grignard reagent with the linear formula FC₆H₃(CH₃)MgCl and a molecular weight of 168.88. Supplied at 0.5 M in THF, this organometallic compound is primarily utilised in chemical synthesis. Its reactive nature makes it suitable for introducing the 3-fluoro-2-methylphenyl group into various organic molecules, facilitating the construction of complex chemical structures in research and development settings.
Organic Synthesis Intermediate
This Grignard reagent serves as a key building block in the synthesis of complex organic molecules. It is employed to introduce the 3-fluoro-2-methylphenyl moiety into target compounds.
Organometallic Chemistry Research
As an organometallic reagent, it is essential for researchers exploring new synthetic methodologies and developing novel chemical entities. Its reactivity profile allows for diverse synthetic transformations.
Pharmaceutical Intermediate Synthesis
The compound can be used in the multi-step synthesis of potential pharmaceutical candidates, where the specific fluorinated aryl group is a desired structural feature.
| Molecular weight | 168.88 |
|---|---|
| Linear formula | FC6H3(CH3)MgCl |
| Boiling point | 65-67 °C(lit.) |
| Density | 0.938 g/mL at 25 °C(lit.) |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -17 °C / 1.4 °F |
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37/38-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluoro-2-methylphenylmagnesium chloride solution used for?
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3-Fluoro-2-methylphenylmagnesium chloride solution is used as a Grignard reagent in organic synthesis, particularly for introducing the 3-fluoro-2-methylphenyl group into target molecules during chemical research and development.
What is the CAS number and linear formula for this product?
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The CAS number is 480424-74-6 and the linear formula is FC₆H₃(CH₃)MgCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a 0.5 M solution in THF. We do not claim specific purity grades (e.g., USP, BP, EP) unless explicitly stated in the product specifications. For detailed assay information, please refer to the product specification sheet.
What are the primary safety hazards associated with this chemical?
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This solution is a highly flammable liquid and vapour (H225) and causes severe skin burns and eye damage (H314). It may also cause respiratory irritation (H335) and is suspected of causing cancer (H351). It can also form explosive peroxides.
How is 3-Fluoro-2-methylphenylmagnesium chloride solution shipped and exported?
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This product is shipped and exported in accordance with international regulations for hazardous materials, including UN 2924, Hazard Class 8(3), Packing Group II. Please consult our shipping department for specific export details.
How can I request a sample or a quote?
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To request a sample or a quote, please contact our sales team through the website or by calling our customer service line, providing the product name and CAS number.
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