Cilostamide
Cilostamide (CAS: 68550-75-4), a bioactive small molecule with the formula C20H26N2O3 and a molecular weight of 342.43 g/mol, is a selective phosphodiesterase III inhibitor. It is primarily utilised in research for its effects on cyclic nucleotide metabolism and cell signalling pathways. This compound serves as a valuable biochemical reagent for studying enzymatic activity and related biological processes, particularly within neuroscience and cell biology research contexts.
- IUPAC
- 6-[3-(N-Cyclohexyl-N-methylcarbamoyl)propoxy]quinolin-2[1H]-one,OPC 3689
- Synonyms
- 6-[3-(N-Cyclohexyl-N-methylcarbamoyl)propoxy]quinolin-2[1H]-oneOPC 3689

Phosphodiesterase III Inhibition
Cilostamide acts as an inhibitor of Phosphodiesterase III (PDE3), an enzyme crucial for cyclic nucleotide metabolism. This makes it a key research tool for investigating the roles of cyclic AMP (cAMP) and cyclic GMP (cGMP) in cellular functions.
Cell Signaling Research
Due to its influence on intracellular signaling pathways mediated by cyclic nucleotides, Cilostamide is employed in studies of cell signalling, particularly in areas related to cardiovascular function and neuronal activity.
Biochemical Research Reagent
As a well-characterised biochemical reagent, Cilostamide is used in laboratory settings to explore enzyme kinetics, drug discovery, and to probe the physiological effects of PDE inhibition.
| Molecular weight | 342.43 |
|---|---|
| Empirical formula | C20H26N2O3 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... PDE3A(5139), PDE3B(5140), PDE5A(8654), PDE7A(5150)rat ... Pde2a(81743), Pde4a(25638) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cilostamide used for?
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Cilostamide is used as a research tool for its role as a selective phosphodiesterase III (PDE3) inhibitor, contributing to studies in cell signalling, cyclic nucleotide metabolism, and biochemical research.
What are the CAS number and formula for Cilostamide?
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The CAS number for Cilostamide is 68550-75-4, and its empirical formula is C20H26N2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Cilostamide as a research grade chemical. The specific assay and purity are detailed in the product specifications. We do not represent this product as meeting USP, BP, EP, or other pharmacopoeial standards.
How should Cilostamide be handled safely?
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Handle Cilostamide with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is a risk. Consult the Safety Data Sheet for comprehensive handling information. The WGK Germany classification is 3.
Is Cilostamide a controlled substance?
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The provided data does not indicate that Cilostamide is a scheduled or controlled substance.
How is Cilostamide packed and shipped?
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Cilostamide is carefully packed for secure transit and is exported globally by Tech Serve Solutions in compliance with all relevant shipping regulations.
How can I request a quote or sample for Cilostamide?
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To request a quote or a sample of Cilostamide, please contact our sales team via the website or by telephone, providing the product name and CAS number (68550-75-4).
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