Chromomycin A3 from Streptomyces griseus

CAS 7059-24-7C57H82O26Biochemicals & Reagents

Chromomycin A3 (CAS: 7059-24-7), with the empirical formula C57H82O26 and a molecular weight of 1183.25 g/mol, is an antibiotic isolated from Streptomyces griseus. It belongs to the aureolic acid group and is known for its ability to interfere with DNA synthesis. This compound is primarily utilized in biochemical research and for fluorescence applications due to its DNA-binding properties.

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Chromomycin A3 from Streptomyces griseus (C57H82O26) — chemical structure, CAS 7059-24-7; Life Science, fine chemical supplied by Tech Serve Solutions

AntibioticsAntibiotics A to ZAntibiotics A-FAntibiotics by ApplicationAntiviralAureolic AcidsBioactive Small MoleculesBiochemicals and ReagentsC-CHCell Biology

01 /Applications

Fluorescence Staining

Chromomycin A3 is used as a fluorescent stain for DNA, particularly in cytogenetics and flow cytometry. Its binding to GC-rich regions of DNA allows for specific visualization and analysis of chromosome structures and genetic material.

Biochemical Research

It serves as a valuable tool in molecular biology and biochemistry research. Its mechanism of action, involving DNA intercalation and inhibition of RNA synthesis, is studied to understand cellular processes and develop potential therapeutic agents.

Antineoplastic Agent Research

As an antineoplastic antibiotic, Chromomycin A3 has been investigated for its potential in cancer therapy. Its cytotoxic effects on rapidly dividing cells make it a subject of study for its antiproliferative properties.

02 /Properties

Molecular weight	1183.25
Empirical formula	C57H82O26
Assay	≥95% (HPLC)
Grade	for fluorescence
Storage temperature	−20°C

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Danger

Hazard statements

H300Fatal if swallowed
H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use
P264Wash thoroughly after handling
P301IF SWALLOWED
P308IF exposed or concerned

Protective equipment	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 3462 6.1 / PGI
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T+
Risk statements (R)	61-28
Safety statements (S)	53-28-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

7059-24-7

MDL number

MFCD00043151

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Chromomycin A3 used for?

Chromomycin A3 is used for fluorescence staining of DNA, in biochemical research, and has been investigated for antineoplastic properties due to its interference with DNA synthesis.

What are the CAS number and formula for Chromomycin A3?

The CAS number for Chromomycin A3 is 7059-24-7, and its empirical formula is C57H82O26.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Chromomycin A3 for fluorescence applications with an assay of ≥95% (HPLC). We do not represent this product as USP, BP, or EP grade.

How should Chromomycin A3 be handled?

Chromomycin A3 is a dangerous substance (Danger, H300, H360). Handle with extreme care using appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a suitable respirator. Always consult the safety data sheet before use.