1-(3,4-Dihydro-2H-[1,8]naphthyridin-1-yl)-2,2-dimethyl-propan-1-one
1-(3,4-Dihydro-2H-[1,8]naphthyridin-1-yl)-2,2-dimethyl-propan-1-one (CAS 824429-54-1; molecular formula C13H18N2O; molar mass 218.29 g/mol) is a nitrogen-containing organic building block combining a partially saturated 1,8-naphthyridine core with a pivaloyl (2,2-dimethylpropanoyl) group. Supplied as a research-grade fine chemical, it serves principally as a synthetic intermediate and scaffold in medicinal-chemistry and pharmaceutical research. Tech Serve Solutions supplies and exports this compound to laboratory, discovery and process-development users worldwide.
- Synonyms
- 1-(3,4-Dihydro-2H-[1,8]naphthyridin-1-yl)-2,2-dimethyl-propan-1-one1-(3,4-Dihydro-1,8-naphthyridin-1(2H)-yl)-2,2-dimethylpropan-1-one2,2-dimethyl-1-(3,4-dihydro-2H-1,8-naphthyridin-1-yl)propan-1-one1-pivaloyl-1,2,3,4-tetrahydro-1,8-naphthyridineCAS 824429-54-1
![1-(3,4-Dihydro-2H-[1,8]naphthyridin-1-yl)-2,2-dimethyl-propan-1-one (C13H18N2O) — chemical structure, CAS 824429-54-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F824429-54-1.png&w=3840&q=75)
Pharmaceutical synthesis intermediate
Used as an intermediate in pharmaceutical and medicinal-chemistry research, where its protected tetrahydronaphthyridine framework supports onward functionalisation toward more complex targets.
Organic building block
Functions as a bicyclic nitrogen building block for multi-step organic synthesis, providing a defined scaffold from which substituted naphthyridine derivatives can be prepared.
Protected amine scaffold
The pivaloyl (tert-butylcarbonyl) group masks the ring nitrogen as a stable amide, making the compound useful where a protected, sterically hindered amine intermediate is required.
Discovery and process-development research
Suitable for laboratory-scale discovery chemistry and route-scouting in process development, supporting structure-activity exploration around the 1,8-naphthyridine motif.
| Molecular weight | 218.29 |
|---|---|
| Empirical formula | C13H18N2O |
Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(3,4-Dihydro-2H-[1,8]naphthyridin-1-yl)-2,2-dimethyl-propan-1-one used for?
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It is used mainly as a synthetic intermediate and organic building block in pharmaceutical and medicinal-chemistry research. Its partially saturated 1,8-naphthyridine core, carrying a pivaloyl group on the ring nitrogen, provides a stable scaffold for preparing more elaborate naphthyridine derivatives. We do not represent it for clinical or therapeutic use.
What is the CAS number and molecular formula of 1-(3,4-Dihydro-2H-[1,8]naphthyridin-1-yl)-2,2-dimethyl-propan-1-one?
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The CAS number is 824429-54-1. The empirical formula is C13H18N2O (Hill notation) with a molecular weight of 218.29 g/mol.
What grade and purity does Tech Serve Solutions supply?
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This compound is supplied as a research/technical-grade fine chemical for laboratory and synthesis use. We do not represent it as USP, BP or EP pharmacopoeial grade. A batch-specific certificate of analysis with the assay can be provided on request, and specifications can be confirmed at the time of enquiry.
What are the safety and handling requirements?
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The substance is classified under GHS07 with the signal word Warning and hazard statement H302 (harmful if swallowed); under the older European system it is labelled Xn with risk phrase R22. Avoid ingestion, wear suitable gloves and eye protection, handle in a well-ventilated area and wash hands thoroughly after use. Its water-hazard class is WGK 3 (Germany), so prevent release to drains and watercourses. Always consult the Safety Data Sheet before use.
How is 1-(3,4-Dihydro-2H-[1,8]naphthyridin-1-yl)-2,2-dimethyl-propan-1-one packed, shipped and exported?
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It is packed in tightly closed, suitably labelled containers sized to the order, from gram research quantities upward, with full documentation including a certificate of analysis and Safety Data Sheet. Tech Serve Solutions exports worldwide and arranges packaging and transport in line with applicable dangerous-goods and import requirements for the destination.
How do I request a sample or quote?
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Contact Tech Serve Solutions with the product name or CAS 824429-54-1 and your required quantity and destination. We will confirm availability, current specification and lead time, and provide a formal quotation. Sample requests for evaluation are welcomed where feasible.
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