1-(3,4-Difluorophenyl)piperidin-4-one
1-(3,4-Difluorophenyl)piperidin-4-one (CAS 885275-07-0) is a fluorinated heterocyclic building block with the molecular formula C11H11F2NO and a molar mass of 211.21 g/mol. It pairs a reactive piperidin-4-one ring with a 3,4-difluorophenyl group, giving a versatile ketone scaffold for medicinal chemistry and fine-chemical synthesis. Tech Serve Solutions supplies it as a research-grade intermediate to pharmaceutical, agrochemical and contract-research laboratories worldwide.
- Synonyms
- 1-(3,4-Difluorophenyl)piperidin-4-one1-(3,4-difluorophenyl)-4-piperidinone1-(3,4-difluorophenyl)-4-piperidone4-Piperidinone, 1-(3,4-difluorophenyl)-CAS 885275-07-0C11H11F2NO

Pharmaceutical intermediate
Serves as a fluorinated piperidinone building block in the multistep synthesis of drug candidates and active pharmaceutical ingredients. The 4-keto group offers a convenient handle for reductive amination, condensation and further ring elaboration.
Fluorinated building block
The 3,4-difluorophenyl moiety introduces fluorine into target molecules, a common strategy for tuning metabolic stability, lipophilicity and binding. This makes the compound useful for structure-activity studies in discovery chemistry.
Heterocyclic scaffold for synthesis
The piperidin-4-one core is a recognised precursor to substituted piperidines, spirocycles and related N-heterocycles. It is widely used to assemble more complex ring systems in fine-chemical and research workflows.
Research and laboratory reagent
Used by academic and industrial laboratories as a reference and reactive intermediate for method development, route scouting and small-scale synthesis. It is supplied for research and manufacturing use, not for direct therapeutic application.
| Molecular weight | 211.21 |
|---|---|
| Empirical formula | C11H11F2NO |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(3,4-Difluorophenyl)piperidin-4-one used for?
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It is used mainly as a fluorinated heterocyclic building block in organic and medicinal chemistry. The reactive piperidin-4-one ketone allows reductive amination, condensation and further functionalisation, making it a useful intermediate for synthesising substituted piperidines and fluorine-containing drug candidates.
What is the CAS number and molecular formula of 1-(3,4-Difluorophenyl)piperidin-4-one?
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Its CAS number is 885275-07-0 and its molecular formula is C11H11F2NO (Hill notation), corresponding to a molecular weight of 211.21 g/mol. It is also described as a 3,4-difluorophenyl-substituted 4-piperidone.
What grade and purity does Tech Serve Solutions supply?
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We supply 1-(3,4-Difluorophenyl)piperidin-4-one as a research/technical-grade synthesis intermediate. We do not represent it as USP, BP or EP pharmacopoeia grade. Current assay and a batch certificate of analysis are confirmed at the time of enquiry, and specifications can be discussed against your requirement.
How should 1-(3,4-Difluorophenyl)piperidin-4-one be handled and stored?
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No GHS classification was provided with this listing, so it should be treated as a research chemical of undetermined hazard. Handle only with suitable laboratory controls, gloves, eye protection and adequate ventilation, keep containers tightly closed in a cool, dry, well-ventilated place, and consult our Safety Data Sheet before use.
How is 1-(3,4-Difluorophenyl)piperidin-4-one packed, shipped and exported?
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It is packed in appropriately sealed, labelled containers sized from gram research quantities to larger bulk orders, with packaging matched to the volume and destination. As a global supplier and exporter since 1998, Tech Serve Solutions arranges compliant documentation and international shipping in line with the applicable transport regulations.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, intended use and destination, and our team will confirm current availability, lead time, specifications and a formal quotation. Samples can be arranged on request, subject to availability.
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