(S)-1-Boc-piperidine-3-carboxylic acid
(S)-1-Boc-piperidine-3-carboxylic acid (CAS: 88495-54-9, C11H19NO4) is a valuable chiral building block and heterocyclic compound. With a molecular weight of 229.27 g/mol, this N-Boc protected piperidine derivative is a key intermediate in asymmetric synthesis. Its well-defined stereochemistry makes it an important component in the development of complex organic molecules, particularly in pharmaceutical research and fine chemical synthesis.
- IUPAC
- (S)-Boc-Nip-OH,(S)-Boc-nipecotic acid
- Synonyms
- (S)-Boc-Nip-OH(S)-Boc-nipecotic acid
Asymmetric Synthesis
This compound serves as a crucial chiral synthon in asymmetric synthesis, enabling the stereoselective construction of complex molecular architectures. Its inherent chirality is leveraged in creating enantiomerically pure target molecules.
Pharmaceutical Intermediate
As a heterocyclic building block, (S)-1-Boc-piperidine-3-carboxylic acid is frequently employed in the synthesis of pharmaceutical agents. It provides a functionalised piperidine core for developing novel drug candidates.
Chemical Synthesis
The compound is a versatile reagent in general chemical synthesis, offering a protected piperidine motif with a carboxylic acid functionality. This allows for various synthetic transformations and derivatisations.
Chiral Pool Synthesis
Utilised within chiral pool synthesis strategies, this molecule allows for the introduction of a defined stereocentre into larger, more complex structures. It is a useful starting material for creating enantiopure compounds.
| Molecular weight | 229.27 |
|---|---|
| Empirical formula | C11H19NO4 |
| Assay | 97% |
| Optical activity | [α]22/D +57°, c = 1 in chloroform |
| Melting point | 165-169 °C |
Hazard statements
- H319Causes serious eye irritation
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
- P305IF IN EYES
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | N |
| Risk statements (R) | 50 |
| Safety statements (S) | 61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-1-Boc-piperidine-3-carboxylic acid used for?
+
(S)-1-Boc-piperidine-3-carboxylic acid is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the chemical and pharmaceutical industries for the development of complex organic molecules.
What is the CAS number and formula for (S)-1-Boc-piperidine-3-carboxylic acid?
+
The CAS number is 88495-54-9 and the empirical formula (Hill notation) is C11H19NO4.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (S)-1-Boc-piperidine-3-carboxylic acid with an assay of 97%. This product is typically supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should (S)-1-Boc-piperidine-3-carboxylic acid be handled?
+
Handle with care. This compound can cause eye irritation (H319) and is very toxic to aquatic life (H400). Wear eyeshields and gloves. Ensure good ventilation and avoid release to the environment. Refer to the Safety Data Sheet (SDS) for comprehensive handling and safety information.
Is (S)-1-Boc-piperidine-3-carboxylic acid a controlled substance?
+
The provided data does not indicate that (S)-1-Boc-piperidine-3-carboxylic acid is a controlled substance.
How is this chemical shipped and exported?
+
As per UN 3077, this chemical is shipped as a Class 9, Packing Group III material. Tech Serve Solutions is a specialist global supplier and exporter, equipped to handle international shipments of fine chemicals.
How can I request a sample or quote for (S)-1-Boc-piperidine-3-carboxylic acid?
+
Please contact our sales team via the website or direct email to request a sample or obtain a quotation for (S)-1-Boc-piperidine-3-carboxylic acid. Please provide your specific requirements and shipping details.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis