(S)-1-Boc-3-hydroxypiperidine
(S)-1-Boc-3-hydroxypiperidine (CAS: 143900-44-1; Formula: C10H19NO3) is a chiral building block essential for asymmetric synthesis. With a molecular weight of 201.26 g/mol, this compound serves as a versatile intermediate in the creation of complex organic molecules. Its piperidine core, functionalized with a hydroxyl group and protected by a Boc moiety, makes it valuable for introducing specific stereochemistry in pharmaceutical and fine chemical research and development.
- IUPAC
- (S)-tert-Butyl 3-hydroxypiperidine-1-carboxylate

Asymmetric Synthesis
Utilised as a chiral precursor for the stereoselective synthesis of complex molecules. Its inherent chirality allows for the construction of enantiomerically pure target compounds.
Pharmaceutical Intermediates
A key building block in the development pathway for novel pharmaceutical agents. Its structure is incorporated into molecules aimed at various therapeutic targets.
Organic Synthesis
Serves as a versatile synthon in general organic chemistry for creating functionalized heterocyclic compounds. It offers a protected piperidine ring with a reactive hydroxyl group.
Chiral Pool Synthesis
Contributes to the chiral pool, providing a readily available source of enantiopure piperidine derivatives for advanced synthetic strategies.
| Molecular weight | 201.26 |
|---|---|
| Empirical formula | C10H19NO3 |
| Assay | 97% |
| Optical activity | [α]22/D +10.0°, c = 1 in chloroform |
| Melting point | 34-40 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-1-Boc-3-hydroxypiperidine used for?
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(S)-1-Boc-3-hydroxypiperidine is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the development of pharmaceuticals and other complex organic molecules.
What is the CAS number and chemical formula for (S)-1-Boc-3-hydroxypiperidine?
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The CAS number is 143900-44-1 and the chemical formula is C10H19NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-1-Boc-3-hydroxypiperidine with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for (S)-1-Boc-3-hydroxypiperidine?
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This compound is a Warning product that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95 US), eyeshields, and gloves, should be used. Ensure adequate ventilation.
How is (S)-1-Boc-3-hydroxypiperidine packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports (S)-1-Boc-3-hydroxypiperidine in compliance with all relevant international regulations for chemical substances. Details on packaging options are available upon request.
How can I request a sample or quote for (S)-1-Boc-3-hydroxypiperidine?
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To request a sample or a quote, please use the contact form on our website or reach out to our sales team directly, referencing the product name and CAS number.
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