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(S)-1-Boc-3-hydroxypiperidine

CAS 143900-44-1C10H19NO3Chemical Synthesis

(S)-1-Boc-3-hydroxypiperidine (CAS: 143900-44-1; Formula: C10H19NO3) is a chiral building block essential for asymmetric synthesis. With a molecular weight of 201.26 g/mol, this compound serves as a versatile intermediate in the creation of complex organic molecules. Its piperidine core, functionalized with a hydroxyl group and protected by a Boc moiety, makes it valuable for introducing specific stereochemistry in pharmaceutical and fine chemical research and development.

IUPAC
(S)-tert-Butyl 3-hydroxypiperidine-1-carboxylate
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(S)-1-Boc-3-hydroxypiperidine (C10H19NO3) — chemical structure, CAS 143900-44-1; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral Building BlocksHeterocyclic Building BlocksPiperidines
01 /Applications

Asymmetric Synthesis

Utilised as a chiral precursor for the stereoselective synthesis of complex molecules. Its inherent chirality allows for the construction of enantiomerically pure target compounds.

Pharmaceutical Intermediates

A key building block in the development pathway for novel pharmaceutical agents. Its structure is incorporated into molecules aimed at various therapeutic targets.

Organic Synthesis

Serves as a versatile synthon in general organic chemistry for creating functionalized heterocyclic compounds. It offers a protected piperidine ring with a reactive hydroxyl group.

Chiral Pool Synthesis

Contributes to the chiral pool, providing a readily available source of enantiopure piperidine derivatives for advanced synthetic strategies.

02 /Properties
Molecular weight201.26
Empirical formulaC10H19NO3
Assay97%
Optical activity[α]22/D +10.0°, c = 1 in chloroform
Melting point34-40 °C
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Flash point>110 °C / >230 °F
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
143900-44-1
MDL number
MFCD04115307
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-1-Boc-3-hydroxypiperidine used for?

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(S)-1-Boc-3-hydroxypiperidine is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the development of pharmaceuticals and other complex organic molecules.

What is the CAS number and chemical formula for (S)-1-Boc-3-hydroxypiperidine?

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The CAS number is 143900-44-1 and the chemical formula is C10H19NO3.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (S)-1-Boc-3-hydroxypiperidine with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

What are the safety and handling precautions for (S)-1-Boc-3-hydroxypiperidine?

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This compound is a Warning product that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95 US), eyeshields, and gloves, should be used. Ensure adequate ventilation.

How is (S)-1-Boc-3-hydroxypiperidine packed, shipped, and exported?

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Tech Serve Solutions packs, ships, and exports (S)-1-Boc-3-hydroxypiperidine in compliance with all relevant international regulations for chemical substances. Details on packaging options are available upon request.

How can I request a sample or quote for (S)-1-Boc-3-hydroxypiperidine?

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To request a sample or a quote, please use the contact form on our website or reach out to our sales team directly, referencing the product name and CAS number.

Need (S)-1-Boc-3-hydroxypiperidine in a specific grade or volume?