(S)-1-Boc-3-methylpiperazine
(S)-1-Boc-3-methylpiperazine (CAS: 147081-29-6, Formula: C10H20N2O2) is a chiral building block and heterocyclic compound. With a molecular weight of 200.28 g/mol, this tert-butyl carbamate protected piperazine derivative is a key reactant in the synthesis of various biologically active molecules. Its applications span the development of potential therapeutics for conditions including HIV/AIDS, obesity, and pain management, making it valuable in pharmaceutical research and development.
- IUPAC
- tert-Butyl (S)-3-methyl-1-piperazinecarboxylate
Synthesis of CCR5 Antagonists
This compound serves as a crucial intermediate in the synthesis of CCR5 antagonists, which are investigated for their potential in treating HIV-1 infection by blocking viral entry into host cells.
Development of Opioid Receptor Antagonists
It is employed in the synthetic pathways leading to novel opioid receptor antagonists, contributing to research efforts aimed at developing new pain management strategies and addiction therapies.
Human Growth Hormone Secretagogue Receptor Antagonists
The molecule is utilized in the creation of antagonists for the human growth hormone secretagogue receptor, a target for potential obesity treatments.
Fatty Acid Oxidation Inhibitors
This piperazine derivative is a reactant in the synthesis of compounds designed to inhibit fatty acid oxidation, which may have implications for metabolic disorder research.
| Molecular weight | 200.28 |
|---|---|
| Empirical formula | C10H20N2O2 |
| Optical activity | [α]/D -16±2°, c = 1 in dioxane |
| Application | Reactant involved in the synthesis of biologically activy molecules including:• CCR5 antagonists with anti-HIV-1 activity1,2• Opioid receptor antagonists3• Human growth hormone secretagogue receptor antagonists for treatment of obesity4• Fatty acid oxidation inhibitors5 |
Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-1-Boc-3-methylpiperazine used for?
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(S)-1-Boc-3-methylpiperazine is used as a reactant in the synthesis of biologically active molecules, including CCR5 antagonists for anti-HIV-1 activity, opioid receptor antagonists, human growth hormone secretagogue receptor antagonists for obesity treatment, and fatty acid oxidation inhibitors.
What is the CAS number and formula for (S)-1-Boc-3-methylpiperazine?
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The CAS number is 147081-29-6 and the empirical formula is C10H20N2O2.
What grade and purity does Tech Serve Solutions supply for (S)-1-Boc-3-methylpiperazine?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific assay and purity information is available on the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
How should (S)-1-Boc-3-methylpiperazine be handled safely?
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Based on GHS information, (S)-1-Boc-3-methylpiperazine is classified as Danger, with hazards H315 (Causes skin irritation), H318 (Causes serious eye damage), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used. Handle in a well-ventilated area or fume hood. Ensure safety statements P261, P280, and P305 + P351 + P338 are followed.
Is (S)-1-Boc-3-methylpiperazine a controlled substance?
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There is no information in the provided data to indicate that (S)-1-Boc-3-methylpiperazine is a controlled substance.
How is (S)-1-Boc-3-methylpiperazine packed and shipped?
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Tech Serve Solutions, as a global supplier and exporter, packages and ships fine chemicals adhering to international regulations. Specific packaging details depend on quantity and destination. Please contact us for export inquiries.
How can I request a sample or quote for (S)-1-Boc-3-methylpiperazine?
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To request a sample or a quotation for (S)-1-Boc-3-methylpiperazine, please contact our sales team through the website or by phone. Provide your contact details and the required quantity.
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